Publications

2016

Scherer M, Koch HM, Schütze A, Pluym N, Krnac D, Gilch G, Leibold E, Scherer G (2016) Human metabolism and excretion kinetics of the fragrance lysmeral after a single oral dosage. Int J Hyg Environ Health 2016 Sep 12; doi: 10.1016/j.ijheh.2016.09.005.


Pluym N, Krnac D, Gilch G, Scherer M, Leibold E, Scherer G (2016) A liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the human biomonitoring of non-occupational exposure to the fragrance 2-(4-tert-butylbenzyl)propionaldehyde (lysmeral). Anal Bioanal Chem. 2016 Aug 408(21), 5873-82; doi: 10.1007/s00216-016-9702-x.

 

 

2015

Pluym N, Gilch G, Scherer G, Scherer M (2015) Analysis of 18 urinary mercapturic acids by two high-throughput multiplex-LC-MS/MS methods. Anal Bioanal Chem. 2015 May 3; Epub ahead of print; doi: 10.1007/s00216-015-8719-x.

 

2014

Michalke B, Rossbach B, Göen T, Schäferhenrich A, Scherer G (2014) Saliva as a matrix for human biomonitoring in occupational and environmental medicine. Int Arch Occup Environ Health. 2015 Jan;88(1):1-44.

 

Markus Piller, Gerhard Gilch, Gerhard Scherer, Max Scherer (2014) Simple, fast and sensitive LC-MS/MS analysis for the simultaneous quantification of nicotine and 10 of its major metabolites. Journal of Chromatography B, March 1st, (951-52) 7-15.

 

Daniel C. Müller, Christian Degen, Gerhard Scherer, Gerhard Jahreis, Reinhard Niessner, Max Scherer (2014) Metabolomics using GC-TOF-MS followed by subsequent GC-FID and HILIC-MS/MS revealed significantly altered fatty acid and phospholipid species profiles in plasma of smokers. J Chromatogr B Analyt Technol Biomed Life Sci. (966), 117-26

 

Mueller DC, Piller M, Niessner R, Scherer M, Scherer G (2014) Untargeted Metabolomic Profiling in Saliva of Smokers and Nonsmokers by a Validated GC-TOF-MS Method. Journal of Proteome Research, 13(3), 1602-1613.

 

Scherer G, Lee PN (2014) Smoking behaviour and compensation: A review of the literature with meta-analysis. Regulatory Toxicology and Pharmacology, 70 (3), 615-628.

 

2012

 

Katharina Sterz; Gerhard Scherer; Jan Krumsiek; Fabian J. Theis; Josef Ecker (2012)  Identification and Quantification of 1-Hydroxybutene-2-yl Mercapturic Acid in Human Urine by UPLC- HILIC-MS/MS as a Novel Biomarker for 1,3-Butadiene Exposure. Chem. Res. Toxicol., 25, 1565-1567

 

Ecker J (2012). Profilling eicosanoids and phospholipids using LC-MS/MS: Principles and recent applications. Journal of Separation Science (JSS), 35, 1227-1237

 

Ecker J, Scherer M, Schmitz G, Liebisch G. (2012) A rapid GC-MS method for quantification of positional and geometric isomers of fatty acid methyl esters.  Journal of Chromatography B (897) 98-104

 

Sterz K, Scherer G, Ecker J. (2012) A simple and robust UPLC-SRM/MS method to quantify urinary eicosanoids. Journal of Lipid Research (JLR), 53(5), 1026-36

 

2011

Degen C, Ecker J, Piegholdt S, Liebisch G, Schmitz G, Jahreis G. (2011) Metabolic and growth inhibitory effects of conjugated fatty acids in the cell line HT-29 with special regard to the conversion of t11,t13-CLA. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 1811(12), 1070-80

 

Minet E, Cheung F, Errington G, Sterz K, Scherer G. (2011) Urinary excretion of the acrylonitrile metabolite 2-cyanoethylmercapturic acid is correlated with a variety of biomarkers of tobacco smoke exposure and consumption. Biomarkers, 16(1), 89-96

 

Ramsauer B, Sterz K, Hagedorn HW, Engl J, Scherer G, McEwan M, Errington G, Shepperd J, Cheung F. (2011) A liquid chromatography/tandem mass spectrometry (LC-MS/MS) method for the determination of phenolic polycyclic aromatic hydrocarbons (OH-PAH) in urine of non-smokers and smokers. Analytical and Bioanalytical Chemistry, 399(2), 877-889

2010

Scherer G, Urban M, Hagedorn HW, Serafin R, Feng S, Kapur S, Muhammad R, Jin Y, Sarkar M, Roethig HJ. (2010) Determination of methyl-, 2-hydroxyethyl- and 2-cyanoethylmercapturic acids as biomarkers of exposure to alkylating agents in cigarette smoke. Journal of Chromatography B, 878(12), 2520-2528

 

Sterz K, Köhler D, Schettgen T, Scherer G. (2010) Enrichment and properties of urinary pre-S-phenylmercapturic acid (pre-SPMA). Journal of Chromatography B, 878(27), 2502-2505

2009

Hagedorn,H.W., Scherer,G., Engl,J., Riedel,K., Cheung,F., Errington,G., Shepperd,J., and McEwan,M. (2009) Urinary Excretion of Phenolic Polycyclic Aromatic Hydrocarbons (OH-PAH) in Nonsmokers and in Smokers of Cigarettes with Different ISO Tar Yields. Journal of Analytical Toxicology, 33 (6), 301-9l.

Kavvadias,D., Scherer,G., Urban,M., Shepperd,J., Cheung,F., Errington,G., and McEwan,M. (2009) Simultaneous determination of four tobacco-specific N-nitrosamines (TSNA) in human urine. Journal of Chromatography B, 877, 1185-1192.

 

Kavvadias D, Scherer G, Cheung F, Errington G, Shepperd J, McEwan M. (2009) Determination of tobacco-specific N-nitrosamines in urine of smokers and non-smokers. Biomarkers, 14(8), 547-553

 

Tricker AR, Schorp MK, Urban HJ, Leyden D, Hagedorn HW, Engl J, Urban M, Riedel K, Gilch G, Janket D, Scherer G. (2009) Comparison of environmental tobacco smoke (ETS) concentrations generated by an electrically heated cigarette smoking system and a conventional cigarette. Inhalation Toxicology 21(1), 62-77

 

Urban,M., Scherer,G., Kavvadias,D., Hagedorn,H.W., Feng,S., Serafin,R., Kapur,S., Muhammad,R., Yin,Y., Mendes,P., and Roethig,H. (2009) Quantitation of N'-Nitrosonornicotine (NNN) in Smokers'Urine by Liquid Chromatography– Tandem Mass Spectrometry. Journal of Analytical Toxicology, 33, 260-265.

2008

Scherer,G., Urban,M., Hagedorn,H.W., Feng,S., Kinser,R., Sarkar,M., Liang,Q., and Roethig,H.J. (2007) Determination of two mercapturic acids related to crotonaldehyde in human urine: Influence of smoking. Human and Experimental Toxicology, 26, 37-47.

 

Tricker,A.R., Schorp,M.K., Urban,H.J., Leyden,D., Hagedorn,H.W., Engl,J., Urban,M., Riedel,K., Gilch,G., Janket,D., and Scherer,G. (2008) Comparison of Environmental Tobacco Smoke (ETS) Concentrations Generated by an Electrically Heated Cigarette Smoking System and a Conventional Cigarette. Inhal.Toxicol., 21, 62-77.

2007

Scherer,G., Engl,J., Urban,M., Gilch,G., Janket,D., and Riedel,K. (2007) Relationship between machine-derived smoke yields and biomarkers in cigarette smokers in Germany. Regulatory Toxicology and Pharmacology, 47, 171-183.

 

Scherer,G., Urban,M., and Hagedorn,H.W. (2007) Biomarkers of the tobacco smoke-related exposure to acrylonitrile. CORESTA Information Bulletin, SSPT Meeting, 2007, Jeju, Korea.

Scherer,G., Engl,J., Urban,M., Gilch,G., Janket,D., and Riedel,K. (2007) Relationship between machine-derived smoke yields and biomarkers in cigarette smokers in Germany. Regul.Toxicol.Pharmacol., 47, 171-183.

 

Scherer,G., Urban,M., Hagedorn,H.W., Feng,S., Kinser,R., Sarkar,M., Liang,Q., and Roethig,H.J. (2007) Determination of two mercapturic acids related to crotonaldehyde in human urine: Influence of smoking. Human and Experimental Toxicology, 26, 37-47.

2006

Feng, S., Roethig, H. J., Liang, Q., Oliveri, D., and Scherer, G. Analysis of urinary 4-aminobiphenyl, 2-aminonaphthalene, and o-toluidine as biomarkers of exposure to cigarette smoke. 35th Annual Meeting of the American College of Clinical Pharmacology, Cambridge, Massachusetts, Sept., 2006 . 2006.

 

Feng,S., Roethig,H.J., Liang,Q., Kinser,R., Jin,Y., Scherer,G., Urban,M., Engl,J., and Riedel,K. (2006) Evaluation of urinary 1-hydroxypyrene, S-phenylmercapturic acid, trans,trans-muconic acid, 3-methyladenine, 3-ethyladenine, 8-hydroxy-2'-deoxyguanosine and thioethers as biomarkers of exposure to cigarette smoke. Biomarkers, 11, 28-52.

 

Riedel,K., Scherer,G., Engl,J., Hagedorn,H.W., and Tricker,A.R. (2006) Determination of three carcinogenic aromatic amines in urine of smokers and non-smokers. Journal of Analytical Toxicology, 30, 187-195

 

Riedel,K., Scherer,G., Engl,J., Hagedorn,H.W., and Tricker,A.R. (2006) Determination of three carcinogenic aromatic amines in urine of smokers and nonsmokers. J.Anal.Toxicol., 30, 187-195.

 

Scherer,G., Gilch,G., Hagedorn,H.W., and Tricker,A.R. (2006) Urinary excretion of ethenoadenine and ethenocytosine by smokers and nonsmokers. European Journal of Molecular and Genetic Toxicology, 169 (1), 72-81.

 

Scherer, G., Hagedorn, H. W., Urban, M., Engl, J., and Kavvadias, D. Is Exhaled Breath Condensate (EBC) A Suitable Biological Matrix for the Determination of Smoking-Related Biomarkers of Early Biological Effects?  2006.  CORESTA Congress, Paris, France, October 15 - 20, 2006.

Scherer,G. (2006) Carboxyhemoglobin and thiocyanate as biomarkers of exposure to carbon monoxide and hydrogen cyanide in tobacco smoke. Exp.Toxicol.Pathol., 58, 101-124.

 

Scherer,G. (2006) Application of biomarkers for the evaluation of potential reduced-exposure products (PREPs). Recent Advances in Tobacco Science, 32, 85-122.

 

Scherer,G., Urban,M., Engl,J., Hagedorn,H.W., and Riedel,K. (2006) Influence of smoking charcoal filter tipped cigarettes on various biomarkers of exposure. Inhalation Toxicology, 18, 821-829.

 

Urban,M., Kavvadias,D., Riedel,K., Scherer,G., and Tricker,A.R. (2006) Urinary mercapturic acids and a hemoglobin adduct for the dosimetry of acrylamide exposure in smokers and non-smokers. Inhalation Toxicology, 18, 831-839.

2005

Scherer, G., Hagedorn, H. W., Urban, M., Engl, J., and Riedel, K. Influence of smoking charcoal filter tipped cigarettes on the uptake of benzene and 1,3-butadiene.  2005.  CORESTA Meeting, Smoke Science/Product Technology Groups, Stratford-upon-Avon, UK, September 4 - 8, 2005.

 

Scherer,G. (2005) Tobacco Smoke: Methodology for assessing the exposure. Central European Journal of Occupational and Environmental Medicine, 11, 102-122.

 

Scherer,G. (2005) Biomonitoring of inhaled complex mixtures - Ambient air, diesel exhaust and cigarette smoke. Experimental and Toxicologic Pathology, 57, 75-110.

 

Scherer, G., Hagedorn, H. W., Urban, M., Engl, J., and Riedel, K. Influence of smoking charcoal filter tipped cigarettes on the uptake of benzene and 1,3-butadiene.  2005.  CORESTA Meeting, Smoke Science/Product Technology Groups, Stratford-upon-Avon, UK, September 4 - 8, 2005.