Biomarker Analysis and Biomonitoring

We provide a range of validated LC-MS and GC-MS methods for accurate determination of environmental chemicals in biological samples such as urine and plasma. Our methods have been used in various HBM campaigns for exposure assessment of environmental chemicals such as VOCs, PAHs, nicotine, phthalates, pesticides and fragrances. Our non-targeted high resolution MS platform is utilized in exposomics - the comprehensive exploration of exposure, their sources and exposure-related health implications. Our aim is to enhance understanding of the interaction of our exposure to chemicals with the human body, promoting health and sustainability.

With 40 years of experience, ABF is a global leader in bioanalysis of exposure biomarkers related to tobacco and new nicotine products. We've analyzed samples for numerous studies, using the largest set of validated methods in tobacco harm reduction. Our clients benefit from our ISO 17025-accredited and GCP/GLP-compliant procedures for biomarker and nicotine PK analysis in regulatory submissions to FDA for Premarket Tobacco Applications (PMTA) and Modified Risk Tobacco Product Applications (MRTPA). We continuously develop new methods and strive to stay scientifically updated, for instance applying our non-targeted high-resolution MS methods to identify product-use specific exposure. Our goal is to responsibly assist clients in introducing new nicotine products.

ABF leads scientific development with innovative methods for precise cannabis and cannabinoids analysis. Our GLP and GCP compliant assays comprise THC, CBD, CBG, and THCV as well as their metabolites in plasma for pharmacokinetic and toxicokinetic studies, exposure assessment, and risk evaluation. We aim to support responsible introduction of new products. Choose ABF for accurate and sensitive cannabinoid bioanalysis.

As an ISO 17025 accredited and GLP certified lab, we provide the pharmaceutical industry with a full range of bioanalytical services, supporting all stages of drug development. Our expertise spans PK/TK/PD studies, metabolite profiling, non-targeted screening, biomarker analysis, and impurity identification using advanced LC-MS technologies. With decades of experience, we ensure quality, accuracy, and swift project turnaround. Our automated data processes make us your top choice for bioanalytical services.