Around 144 cannabinoids have been identified in cannabis plant, among them tetrahydrocannabinol (THC) and cannabidiol (CBD) are the most prominent ones. The market for cannabis and cannabinoids has experienced significant growth in recent years, driven by a combination of changing regulatory landscapes, increasing consumer demand and growing recognition of the potential health and wellness benefits associated with these compounds.
As a cutting-edge laboratory, ABF is at the forefront of this scientific journey and has already developed methods for the bioanalysis of cannabis and cannabinoids. These methods are characterized by its level of sensitivity, automation, throughput and can be used for pharmacokinetic studies, exposure assessment and risk evaluation.
Our Commitment
Extensive expertise in the analysis of biological samples for both clinical and non-clinical studies
Uncompromising Quality, Compliance, and Data Integrity
Timely and Accurate Analysis & Reporting Supporting Decision-Making and Research Efforts
Using innovative LC-MS/MS techniques, our specialised services are designed to accurately quantify relevant cannabionids and their metabolites in a variety of biological matrices. ABF offers an ultra-sensitive, cost-efficient, high-throughput analytical method following ICH M10 guidelines and GLP/GCP principles.
Our laboratory is ISO 17025 accredited and adheres to GLP/GCP compliance for the highest regulatory standards. This allows us to support your research from early stage pharmacokinetic studies through to regulated GCP studies.
Trusted Bioanalytical Services Tailored to Your Specific Application
Trusted Bioanalytical Services Tailored to Your Specific Application
ABF's expert team has a strong reputation, dedicated to innovative method development and high-quality bioanalytical services tailored to each client.
Our ISO17025 accredited, GLP-certified, and GCP-compliant lab adheres to strict global regulatory guidelines, meeting industry standards. We analyze biological samples (urine, blood, saliva) in (pre-) clinical trials using validated methods, following ICH M10, EMA, FDA, and OECD guidelines.
To ensure sample integrity, our spacious sample storage facilities, equipped with fridges and freezers, are monitored 24/7.
ABF offers comprehensive support during the bioanalytical phase of clinical trials with Analytical Chemists, responsible Scientists, and a dedicated Quality Assurance unit.
Integrated Solutions for Seamless Sample Management World Wide
Integrated Solutions for Seamless Sample Management World Wide
We provide integrated solutions for global studies, supporting you from sample shipment to results delivery.
Leveraging our extensive global network of carrier services, we ensure smooth and efficient delivery of biological samples worldwide.
Benefit from expertise to streamline your research process and accelerate your study timelines.
Biomarker
Exposure to
Matrix
Analytical Technique
Reference
11-COOH-THC
Tetrahydrocannabinol
Plasma
LC-MS/MS
Conference contribution
October 2024
Analysis of 11 endocannabinoids in human plasma using column switching high-performance liquid chromatography–mass spectrometry
Nikola Pluym, Richard Kanis, Therese Brukhardt, Gerhard Scherer, Max Scherer
CORESTA Congress 2024, Edinburgh, UK
11-OH-THC
Tetrahydrocannabinol
Plasma
LC-MS/MS
Conference contribution
October 2024
Analysis of 11 endocannabinoids in human plasma using column switching high-performance liquid chromatography–mass spectrometry
Nikola Pluym, Richard Kanis, Therese Brukhardt, Gerhard Scherer, Max Scherer
CORESTA Congress 2024, Edinburgh, UK
6-Hydroxycannabidiol (6-OH-CBD)
Cannabidiol
Plasma
LC-MS/MS
Conference contribution
October 2024
Analysis of 11 endocannabinoids in human plasma using column switching high-performance liquid chromatography–mass spectrometry
Nikola Pluym, Richard Kanis, Therese Brukhardt, Gerhard Scherer, Max Scherer
CORESTA Congress 2024, Edinburgh, UK
7-Carboxycannabidiol (7-COOH-CBD)
Cannabidiol
Plasma
LC-MS/MS
Conference contribution
October 2024
Analysis of 11 endocannabinoids in human plasma using column switching high-performance liquid chromatography–mass spectrometry
Nikola Pluym, Richard Kanis, Therese Brukhardt, Gerhard Scherer, Max Scherer
CORESTA Congress 2024, Edinburgh, UK
7-Hydroxycannabidiol (7-OH-CBD)
Cannabidiol
Plasma
LC-MS/MS
Conference contribution
October 2024
Analysis of 11 endocannabinoids in human plasma using column switching high-performance liquid chromatography–mass spectrometry
Nikola Pluym, Richard Kanis, Therese Brukhardt, Gerhard Scherer, Max Scherer
CORESTA Congress 2024, Edinburgh, UK
Cannabidiol (CBD)
Cannabidiol
Plasma
LC-MS/MS
Conference contribution
October 2024
Analysis of 11 endocannabinoids in human plasma using column switching high-performance liquid chromatography–mass spectrometry
Nikola Pluym, Richard Kanis, Therese Brukhardt, Gerhard Scherer, Max Scherer
CORESTA Congress 2024, Edinburgh, UK
Cannabielsoin (CBE)
Cannabidiol
Plasma
LC-MS/MS
Conference contribution
October 2024
Analysis of 11 endocannabinoids in human plasma using column switching high-performance liquid chromatography–mass spectrometry
Nikola Pluym, Richard Kanis, Therese Brukhardt, Gerhard Scherer, Max Scherer
CORESTA Congress 2024, Edinburgh, UK
Cannabinol (CBN)
Tetrahydrocannabinol
Plasma
LC-MS/MS
Conference contribution
October 2024
Analysis of 11 endocannabinoids in human plasma using column switching high-performance liquid chromatography–mass spectrometry
Nikola Pluym, Richard Kanis, Therese Brukhardt, Gerhard Scherer, Max Scherer
CORESTA Congress 2024, Edinburgh, UK
Creatinine
Normalization of urinary biomarker concentrations
Urine
Photometry
Tetrahydrocannabinol (THC)
Tetrahydrocannabinol
Plasma
LC-MS/MS
Conference contribution
October 2024
Analysis of 11 endocannabinoids in human plasma using column switching high-performance liquid chromatography–mass spectrometry
Nikola Pluym, Richard Kanis, Therese Brukhardt, Gerhard Scherer, Max Scherer
CORESTA Congress 2024, Edinburgh, UK
Tetrahydrocannabivarin (THCV)
Tetrahydrocannabinol
Plasma
LC-MS/MS
Conference contribution
October 2024
Analysis of 11 endocannabinoids in human plasma using column switching high-performance liquid chromatography–mass spectrometry
Nikola Pluym, Richard Kanis, Therese Brukhardt, Gerhard Scherer, Max Scherer
CORESTA Congress 2024, Edinburgh, UK
THC-glucuronide
Tetrahydrocannabinol
Plasma
LC-MS/MS
Conference contribution
October 2024
Analysis of 11 endocannabinoids in human plasma using column switching high-performance liquid chromatography–mass spectrometry
Nikola Pluym, Richard Kanis, Therese Brukhardt, Gerhard Scherer, Max Scherer
CORESTA Congress 2024, Edinburgh, UK
Pioneers in biomarker research
Almost all of the biomarker methods developed at ABF were published in peer-reviewed journals, a fact that supports the validity, transparency and scientific evidence of the bioanalysis especially of importance for regulatory submissions