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Unsere Biomarker Methoden

Biomarker	Exposure to	Matrix	Analytical Technique	Reference
11-dehydro-TXB2	Inflammation	Urine	LC-MS/MS	publication February 2012 A simple and robust UPLC-SRM/MS method to quantify urinary eicosanoids Sterz K, Scherer G, Ecker J Journal of Lipid Research, Volume 53, doi: 10.1194/jlr.D023739 publication March 2018 Analysis of Urinary Eicosanoids by LC-MS/MS Reveals Alterations in the Metabolic Profile after Smoking Cessation Goettel M, Niessner R, Scherer M, Scherer G, Pluym N Chemical Research in Toxicology, Volume 31, doi: 10.1021/acs.chemrestox publication October 2018 Identifying suitable biomarkers of biological effects (BOBEs) for evaluating reduced risk products Scherer G, Pluym N, Scherer M CORESTA Congress 2018, Biomarker Workshop, Kunming, China publication October 2017 Metabolomic Fingerprinting in Various Body Fluids of a Diet-Controlled Clinical Smoking Cessation Study Using a Validated GC-TOF-MS Metabolomics Platform Goettel M, Niessner R, Mueller D, Scherer M, Scherer G, Pluym N Journal of Proteome Research, Volume 16(10), doi: 10.1021/acs.jproteome.7b00128. publication January 2018 Review of biomarkers to assess the effects of switching from cigarettes to modified risk tobacco products Peck MJ, Sanders EB, Scherer G, Luedicke F, Weitkunat R Biomarkers, Volume 23(3), doi: 10.1080/1354750X.2017.1419284 publication April 2018 Suitability of biomarkers of biological effects (BOBEs) for assessing the likelihood of reducing the tobacco related disease risk by new and innovative tobacco products: A literature review Scherer G Regulatory Toxicology and Pharmacology, Volume 94, doi: 10.1016/j.yrtph.2018.02.002
12(S)-HETE	Inflammation	Urine	LC-MS/MS	publication February 2012 A simple and robust UPLC-SRM/MS method to quantify urinary eicosanoids Sterz K, Scherer G, Ecker J Journal of Lipid Research, Volume 53, doi: 10.1194/jlr.D023739 publication March 2018 Analysis of Urinary Eicosanoids by LC-MS/MS Reveals Alterations in the Metabolic Profile after Smoking Cessation Goettel M, Niessner R, Scherer M, Scherer G, Pluym N Chemical Research in Toxicology, Volume 31, doi: 10.1021/acs.chemrestox publication October 2017 Metabolomic Fingerprinting in Various Body Fluids of a Diet-Controlled Clinical Smoking Cessation Study Using a Validated GC-TOF-MS Metabolomics Platform Goettel M, Niessner R, Mueller D, Scherer M, Scherer G, Pluym N Journal of Proteome Research, Volume 16(10), doi: 10.1021/acs.jproteome.7b00128. publication April 2018 Suitability of biomarkers of biological effects (BOBEs) for assessing the likelihood of reducing the tobacco related disease risk by new and innovative tobacco products: A literature review Scherer G Regulatory Toxicology and Pharmacology, Volume 94, doi: 10.1016/j.yrtph.2018.02.002
1,3-Butadiene	Tobacco Smoke	ETS	GC-MS
1-Aminonaphthalene (1-AN)	1-Aminonaphthalene	Urine	GC-MS	publication November 2022 Assessment of the Exposure to Aromatic Amines in Users of Various Tobacco/Nicotine Products Gerhard Scherer, Kirsten Riedel, Nikola Pluym, Max Scherer ACS Omega, doi: 10.1021/acsomega.2c06130 publication April 2006 Determination of three carcinogenic aromatic amines in urine of smokers and nonsmokers Riedel K, Scherer G, Engl J, Hagedorn H-W, Tricker AR Journal of Analytical Toxicology, Volume 30, doi: 10.1093/jat/30.3.187
1-Hydroxyphenanthrene (1-OH-Phe)	Phenanthrene	Urine	LC-MS/MS	publication February 2020 Polycyclic aromatic hydrocarbons (PAH) in urine of children and adolescents in Germany - human biomonitoring results of the German Environmental Survey 2014-2017 (GerES V) Murawski A, Roth A, Schwedler G, Schmied-Tobies MIH, Rucic E, Pluym N, Scherer M, Scherer G, Conrad A, Kolossa-Gehring M International Journal of Hygiene and Environmental Health, Volume 226, doi: 10.1016/j.ijheh.2020.113491 publication November 2010 A liquid chromatography/tandem mass spectrometry (LC-MS/MS) method for the determination of phenolic polycyclic aromatic hydrocarbons (OH-PAH) in urine of non-smokers and smokers Ramsauer B, Sterz K, Hagedorn H-W, Engl J, Scherer G, McEwan M, Errington G, Shepperd J, Cheung F Analytical and Bioanalytical Chemistry, volume 399, doi:10.1007/s00216-010-4355-7 publication August 2022 Assessment of the exposure to polycyclic aromatic hydrocarbons in users of various tobacco/nicotine products by suitable urinary biomarkers Gerhard Scherer, Max Scherer, Nadine Rögner, Nikola Pluym Archives of Toxicology doi.org/10.1007/s00204-022-03349-4 publication October 2022 Time trend of exposure to secondhand tobacco smoke and polycyclic aromatic hydrocarbons between 1995 and 2019 in Germany – Showcases for successful European legislation Therese Burkhardt, Max Scherer, Gerhard Scherer, Nikola Pluym, Till Weber, Marike Kolossa-Gehring Environmental Research, doi: 10.1016/j.envres.2022.114638 Conference contribution September 2022 The impact of European legislation on the reduction of Environmental Tobacco Smoke and Polycyclic Aromatic Hydrocarbons between 1995 and 2019 in Germany Therese Burkhardt, Max Scherer, Gerhard Scherer, Till Weber, Nikola Pluym, Marike Kolossa-Gehring ISES 2022, Lisbon
1-Hydroxypyrene (1-OH-Pyr)	Pyrene	Urine	LC-MS/MS	publication November 2010 A liquid chromatography/tandem mass spectrometry (LC-MS/MS) method for the determination of phenolic polycyclic aromatic hydrocarbons (OH-PAH) in urine of non-smokers and smokers Ramsauer B, Sterz K, Hagedorn H-W, Engl J, Scherer G, McEwan M, Errington G, Shepperd J, Cheung F Analytical and Bioanalytical Chemistry, volume 399, doi:10.1007/s00216-010-4355-7 publication August 2022 Assessment of the exposure to polycyclic aromatic hydrocarbons in users of various tobacco/nicotine products by suitable urinary biomarkers Gerhard Scherer, Max Scherer, Nadine Rögner, Nikola Pluym Archives of Toxicology doi.org/10.1007/s00204-022-03349-4 publication February 2020 Polycyclic aromatic hydrocarbons (PAH) in urine of children and adolescents in Germany - human biomonitoring results of the German Environmental Survey 2014-2017 (GerES V) Murawski A, Roth A, Schwedler G, Schmied-Tobies MIH, Rucic E, Pluym N, Scherer M, Scherer G, Conrad A, Kolossa-Gehring M International Journal of Hygiene and Environmental Health, Volume 226, doi: 10.1016/j.ijheh.2020.113491 publication October 2022 Time trend of exposure to secondhand tobacco smoke and polycyclic aromatic hydrocarbons between 1995 and 2019 in Germany – Showcases for successful European legislation Therese Burkhardt, Max Scherer, Gerhard Scherer, Nikola Pluym, Till Weber, Marike Kolossa-Gehring Environmental Research, doi: 10.1016/j.envres.2022.114638 Conference contribution September 2022 The impact of European legislation on the reduction of Environmental Tobacco Smoke and Polycyclic Aromatic Hydrocarbons between 1995 and 2019 in Germany Therese Burkhardt, Max Scherer, Gerhard Scherer, Till Weber, Nikola Pluym, Marike Kolossa-Gehring ISES 2022, Lisbon
1-Naphthol (1-Hydroxynaphthalene, 1-OH-Nap)	Naphthalene	Urine	LC-MS/MS	publication November 2010 A liquid chromatography/tandem mass spectrometry (LC-MS/MS) method for the determination of phenolic polycyclic aromatic hydrocarbons (OH-PAH) in urine of non-smokers and smokers Ramsauer B, Sterz K, Hagedorn H-W, Engl J, Scherer G, McEwan M, Errington G, Shepperd J, Cheung F Analytical and Bioanalytical Chemistry, volume 399, doi:10.1007/s00216-010-4355-7 publication August 2022 Assessment of the exposure to polycyclic aromatic hydrocarbons in users of various tobacco/nicotine products by suitable urinary biomarkers Gerhard Scherer, Max Scherer, Nadine Rögner, Nikola Pluym Archives of Toxicology doi.org/10.1007/s00204-022-03349-4 publication February 2020 Polycyclic aromatic hydrocarbons (PAH) in urine of children and adolescents in Germany - human biomonitoring results of the German Environmental Survey 2014-2017 (GerES V) Murawski A, Roth A, Schwedler G, Schmied-Tobies MIH, Rucic E, Pluym N, Scherer M, Scherer G, Conrad A, Kolossa-Gehring M International Journal of Hygiene and Environmental Health, Volume 226, doi: 10.1016/j.ijheh.2020.113491 publication October 2022 Time trend of exposure to secondhand tobacco smoke and polycyclic aromatic hydrocarbons between 1995 and 2019 in Germany – Showcases for successful European legislation Therese Burkhardt, Max Scherer, Gerhard Scherer, Nikola Pluym, Till Weber, Marike Kolossa-Gehring Environmental Research, doi: 10.1016/j.envres.2022.114638 Conference contribution September 2022 The impact of European legislation on the reduction of Environmental Tobacco Smoke and Polycyclic Aromatic Hydrocarbons between 1995 and 2019 in Germany Therese Burkhardt, Max Scherer, Gerhard Scherer, Till Weber, Nikola Pluym, Marike Kolossa-Gehring ISES 2022, Lisbon
20-Carboxy-Leukotriene B4	Inflammation	Urine	LC-MS/MS	publication October 2017 Metabolomic Fingerprinting in Various Body Fluids of a Diet-Controlled Clinical Smoking Cessation Study Using a Validated GC-TOF-MS Metabolomics Platform Goettel M, Niessner R, Mueller D, Scherer M, Scherer G, Pluym N Journal of Proteome Research, Volume 16(10), doi: 10.1021/acs.jproteome.7b00128. publication April 2018 Suitability of biomarkers of biological effects (BOBEs) for assessing the likelihood of reducing the tobacco related disease risk by new and innovative tobacco products: A literature review Scherer G Regulatory Toxicology and Pharmacology, Volume 94, doi: 10.1016/j.yrtph.2018.02.002
20-Hydroxy-Leukotriene B4	Inflammation	Urine	LC-MS/MS	publication October 2017 Metabolomic Fingerprinting in Various Body Fluids of a Diet-Controlled Clinical Smoking Cessation Study Using a Validated GC-TOF-MS Metabolomics Platform Goettel M, Niessner R, Mueller D, Scherer M, Scherer G, Pluym N Journal of Proteome Research, Volume 16(10), doi: 10.1021/acs.jproteome.7b00128. publication April 2018 Suitability of biomarkers of biological effects (BOBEs) for assessing the likelihood of reducing the tobacco related disease risk by new and innovative tobacco products: A literature review Scherer G Regulatory Toxicology and Pharmacology, Volume 94, doi: 10.1016/j.yrtph.2018.02.002
2,3-dinor-8-iso-PGF2α	Oxidative Stress	Urine	LC-MS/MS	publication February 2012 A simple and robust UPLC-SRM/MS method to quantify urinary eicosanoids Sterz K, Scherer G, Ecker J Journal of Lipid Research, Volume 53, doi: 10.1194/jlr.D023739 publication March 2018 Analysis of Urinary Eicosanoids by LC-MS/MS Reveals Alterations in the Metabolic Profile after Smoking Cessation Goettel M, Niessner R, Scherer M, Scherer G, Pluym N Chemical Research in Toxicology, Volume 31, doi: 10.1021/acs.chemrestox publication October 2017 Metabolomic Fingerprinting in Various Body Fluids of a Diet-Controlled Clinical Smoking Cessation Study Using a Validated GC-TOF-MS Metabolomics Platform Goettel M, Niessner R, Mueller D, Scherer M, Scherer G, Pluym N Journal of Proteome Research, Volume 16(10), doi: 10.1021/acs.jproteome.7b00128. publication April 2018 Suitability of biomarkers of biological effects (BOBEs) for assessing the likelihood of reducing the tobacco related disease risk by new and innovative tobacco products: A literature review Scherer G Regulatory Toxicology and Pharmacology, Volume 94, doi: 10.1016/j.yrtph.2018.02.002
2,3-dinor-TXB2	Inflammation	Urine	LC-MS/MS	publication February 2012 A simple and robust UPLC-SRM/MS method to quantify urinary eicosanoids Sterz K, Scherer G, Ecker J Journal of Lipid Research, Volume 53, doi: 10.1194/jlr.D023739 publication March 2018 Analysis of Urinary Eicosanoids by LC-MS/MS Reveals Alterations in the Metabolic Profile after Smoking Cessation Goettel M, Niessner R, Scherer M, Scherer G, Pluym N Chemical Research in Toxicology, Volume 31, doi: 10.1021/acs.chemrestox publication October 2018 Identifying suitable biomarkers of biological effects (BOBEs) for evaluating reduced risk products Scherer G, Pluym N, Scherer M CORESTA Congress 2018, Biomarker Workshop, Kunming, China publication October 2017 Metabolomic Fingerprinting in Various Body Fluids of a Diet-Controlled Clinical Smoking Cessation Study Using a Validated GC-TOF-MS Metabolomics Platform Goettel M, Niessner R, Mueller D, Scherer M, Scherer G, Pluym N Journal of Proteome Research, Volume 16(10), doi: 10.1021/acs.jproteome.7b00128. publication January 2018 Review of biomarkers to assess the effects of switching from cigarettes to modified risk tobacco products Peck MJ, Sanders EB, Scherer G, Luedicke F, Weitkunat R Biomarkers, Volume 23(3), doi: 10.1080/1354750X.2017.1419284 publication April 2018 Suitability of biomarkers of biological effects (BOBEs) for assessing the likelihood of reducing the tobacco related disease risk by new and innovative tobacco products: A literature review Scherer G Regulatory Toxicology and Pharmacology, Volume 94, doi: 10.1016/j.yrtph.2018.02.002
2-Aminonaphthalene (2-AN)	2-Aminonaphthalene	Urine, ETS	GC-MS	publication April 2006 Determination of three carcinogenic aromatic amines in urine of smokers and nonsmokers Riedel K, Scherer G, Engl J, Hagedorn H-W, Tricker AR Journal of Analytical Toxicology, Volume 30, doi: 10.1093/jat/30.3.187 publication November 2022 Assessment of the Exposure to Aromatic Amines in Users of Various Tobacco/Nicotine Products Gerhard Scherer, Kirsten Riedel, Nikola Pluym, Max Scherer ACS Omega, doi: 10.1021/acsomega.2c06130
2-(Carboxyl-1-methylethyl)mercapturic acid (CMEMA)	Crotonaldehyde	Urine	LC-MS/MS	Conference contribution October 2014 Analysis of 18 Urinary Mercapturic Acids by two Multiplex-LC-MS/MS Methods Pluym N, Gilch G, Scherer G, Scherer M CORESTA Congress 2014, Quebec, Canada publication May 2015 Analysis of 18 urinary mercapturic acids by two high-throughput multiplex-LC-MS/MS methods Pluym N, Gilch G, Scherer G, Scherer M Analytical and Bioanalytical Chemistry, Volume 407, doi: 10.1007/s00216-015-8719-x publication October 2022 Comparison of urinary mercapturic acid excretions in users of various tobacco/nicotine products Gerhard Scherer, Nikola Pluym, Max Scherer Drug Testing and Analysis DOI: 10.1002/dta.3372
2-Hydroxy-1-phenylethylmercapturic acid (PHEMA 1)	Styrene	Urine	LC-MS/MS	Conference contribution October 2014 Analysis of 18 Urinary Mercapturic Acids by two Multiplex-LC-MS/MS Methods Pluym N, Gilch G, Scherer G, Scherer M CORESTA Congress 2014, Quebec, Canada publication May 2015 Analysis of 18 urinary mercapturic acids by two high-throughput multiplex-LC-MS/MS methods Pluym N, Gilch G, Scherer G, Scherer M Analytical and Bioanalytical Chemistry, Volume 407, doi: 10.1007/s00216-015-8719-x publication October 2022 Comparison of urinary mercapturic acid excretions in users of various tobacco/nicotine products Gerhard Scherer, Nikola Pluym, Max Scherer Drug Testing and Analysis DOI: 10.1002/dta.3372
2-Hydroxy-2-phenylethylmercapturic acid (PHEMA 2)	Styrene	Urine	LC-MS/MS	Conference contribution October 2014 Analysis of 18 Urinary Mercapturic Acids by two Multiplex-LC-MS/MS Methods Pluym N, Gilch G, Scherer G, Scherer M CORESTA Congress 2014, Quebec, Canada publication May 2015 Analysis of 18 urinary mercapturic acids by two high-throughput multiplex-LC-MS/MS methods Pluym N, Gilch G, Scherer G, Scherer M Analytical and Bioanalytical Chemistry, Volume 407, doi: 10.1007/s00216-015-8719-x publication October 2022 Comparison of urinary mercapturic acid excretions in users of various tobacco/nicotine products Gerhard Scherer, Nikola Pluym, Max Scherer Drug Testing and Analysis DOI: 10.1002/dta.3372
2-Hydroxyethylmercapturic acid (HEMA)	Ethylene oxide, Alkylating agents	Urine	LC-MS/MS	Conference contribution October 2014 Analysis of 18 Urinary Mercapturic Acids by two Multiplex-LC-MS/MS Methods Pluym N, Gilch G, Scherer G, Scherer M CORESTA Congress 2014, Quebec, Canada publication May 2015 Analysis of 18 urinary mercapturic acids by two high-throughput multiplex-LC-MS/MS methods Pluym N, Gilch G, Scherer G, Scherer M Analytical and Bioanalytical Chemistry, Volume 407, doi: 10.1007/s00216-015-8719-x Conference contribution October 2018 Analytical methods for the determination of carbonyls in aerosol from e-vapor products and cigarette smoke and their urinary biomarkers of exposure Landmesser A, Scherer M, Scherer G, Pluym N CORESTA Congress 2018, Kunming, China Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients – methods Landmesser A, Pluym N, Scherer G, Sarkar M, Edmiston J, Scherer M CORESTA SSPT 2017, Kitzbühel, Austria Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients–results Landmesser A, Scherer M, Scherer G, Sarkar M, Edmiston J, Pluym N CORESTA SSPT 2017, Kitzbühel, Austria publication October 2022 Comparison of urinary mercapturic acid excretions in users of various tobacco/nicotine products Gerhard Scherer, Nikola Pluym, Max Scherer Drug Testing and Analysis DOI: 10.1002/dta.3372
2-Hydroxyfluorene (2-OH-Flu)	Fluorene	Urine	LC-MS/MS	publication November 2010 A liquid chromatography/tandem mass spectrometry (LC-MS/MS) method for the determination of phenolic polycyclic aromatic hydrocarbons (OH-PAH) in urine of non-smokers and smokers Ramsauer B, Sterz K, Hagedorn H-W, Engl J, Scherer G, McEwan M, Errington G, Shepperd J, Cheung F Analytical and Bioanalytical Chemistry, volume 399, doi:10.1007/s00216-010-4355-7 publication August 2022 Assessment of the exposure to polycyclic aromatic hydrocarbons in users of various tobacco/nicotine products by suitable urinary biomarkers Gerhard Scherer, Max Scherer, Nadine Rögner, Nikola Pluym Archives of Toxicology doi.org/10.1007/s00204-022-03349-4 publication February 2020 Polycyclic aromatic hydrocarbons (PAH) in urine of children and adolescents in Germany - human biomonitoring results of the German Environmental Survey 2014-2017 (GerES V) Murawski A, Roth A, Schwedler G, Schmied-Tobies MIH, Rucic E, Pluym N, Scherer M, Scherer G, Conrad A, Kolossa-Gehring M International Journal of Hygiene and Environmental Health, Volume 226, doi: 10.1016/j.ijheh.2020.113491 Conference contribution September 2022 The impact of European legislation on the reduction of Environmental Tobacco Smoke and Polycyclic Aromatic Hydrocarbons between 1995 and 2019 in Germany Therese Burkhardt, Max Scherer, Gerhard Scherer, Till Weber, Nikola Pluym, Marike Kolossa-Gehring ISES 2022, Lisbon
2-Hydroxyphenanthrene (2-OH-Phe)	Phenanthrene	Urine	LC-MS/MS	publication November 2010 A liquid chromatography/tandem mass spectrometry (LC-MS/MS) method for the determination of phenolic polycyclic aromatic hydrocarbons (OH-PAH) in urine of non-smokers and smokers Ramsauer B, Sterz K, Hagedorn H-W, Engl J, Scherer G, McEwan M, Errington G, Shepperd J, Cheung F Analytical and Bioanalytical Chemistry, volume 399, doi:10.1007/s00216-010-4355-7 publication August 2022 Assessment of the exposure to polycyclic aromatic hydrocarbons in users of various tobacco/nicotine products by suitable urinary biomarkers Gerhard Scherer, Max Scherer, Nadine Rögner, Nikola Pluym Archives of Toxicology doi.org/10.1007/s00204-022-03349-4 publication February 2020 Polycyclic aromatic hydrocarbons (PAH) in urine of children and adolescents in Germany - human biomonitoring results of the German Environmental Survey 2014-2017 (GerES V) Murawski A, Roth A, Schwedler G, Schmied-Tobies MIH, Rucic E, Pluym N, Scherer M, Scherer G, Conrad A, Kolossa-Gehring M International Journal of Hygiene and Environmental Health, Volume 226, doi: 10.1016/j.ijheh.2020.113491 publication October 2022 Time trend of exposure to secondhand tobacco smoke and polycyclic aromatic hydrocarbons between 1995 and 2019 in Germany – Showcases for successful European legislation Therese Burkhardt, Max Scherer, Gerhard Scherer, Nikola Pluym, Till Weber, Marike Kolossa-Gehring Environmental Research, doi: 10.1016/j.envres.2022.114638 Conference contribution September 2022 The impact of European legislation on the reduction of Environmental Tobacco Smoke and Polycyclic Aromatic Hydrocarbons between 1995 and 2019 in Germany Therese Burkhardt, Max Scherer, Gerhard Scherer, Till Weber, Nikola Pluym, Marike Kolossa-Gehring ISES 2022, Lisbon
2-Hydroxypropylmercapturic acid (2-HPMA)	Propylene oxide	Urine	LC-MS/MS	Conference contribution October 2014 Analysis of 18 Urinary Mercapturic Acids by two Multiplex-LC-MS/MS Methods Pluym N, Gilch G, Scherer G, Scherer M CORESTA Congress 2014, Quebec, Canada publication May 2015 Analysis of 18 urinary mercapturic acids by two high-throughput multiplex-LC-MS/MS methods Pluym N, Gilch G, Scherer G, Scherer M Analytical and Bioanalytical Chemistry, Volume 407, doi: 10.1007/s00216-015-8719-x Conference contribution October 2019 Analysis of aldehydes, propylene oxide and glycidol in tobacco smoke and e-cigarette vapor and their respective urinary biomarkers Landmesser A, Scherer G, Pluym N, Scherer M CORESTA SSPT 2019, Hamburg, Germany Conference contribution October 2018 Analytical methods for the determination of carbonyls in aerosol from e-vapor products and cigarette smoke and their urinary biomarkers of exposure Landmesser A, Scherer M, Scherer G, Pluym N CORESTA Congress 2018, Kunming, China publication June 2021 Assessment of the potential vaping-related exposure to carbonyls and epoxides using stable isotope-labeled precursors in the e-liquid Landmesser A, Scherer M, Scherer G, Sarkar M, Edmiston J, Niessner R, Pluym N Archives of Toxicology, doi:10.1007/s00204-021-03097-x Conference contribution February 2018 Biomarkers of exposure specific to e-vapor products based on stable-isotope labeled ingredients Landmesser A, Scherer M, Scherer G, Sarkar M, Edmiston J, Pluym N SRNT 2018, Baltimore, USA Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients – methods Landmesser A, Pluym N, Scherer G, Sarkar M, Edmiston J, Scherer M CORESTA SSPT 2017, Kitzbühel, Austria Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients–results Landmesser A, Scherer M, Scherer G, Sarkar M, Edmiston J, Pluym N CORESTA SSPT 2017, Kitzbühel, Austria publication October 2022 Comparison of urinary mercapturic acid excretions in users of various tobacco/nicotine products Gerhard Scherer, Nikola Pluym, Max Scherer Drug Testing and Analysis DOI: 10.1002/dta.3372 Conference contribution October 2018 Novel biomarkers to characterize exposure to aldehydes from e-vapor products based on stable-isotope constituents Landmesser A, Scherer M, Scherer G, Sarkar M, Edmiston J, Pluym N CORESTA Congress 2018, Kunming, China
2-Naphthol (2-Hydroxynaphthalene, 2-OH-Nap)	Naphthalene	Urine	LC-MS/MS	publication November 2010 A liquid chromatography/tandem mass spectrometry (LC-MS/MS) method for the determination of phenolic polycyclic aromatic hydrocarbons (OH-PAH) in urine of non-smokers and smokers Ramsauer B, Sterz K, Hagedorn H-W, Engl J, Scherer G, McEwan M, Errington G, Shepperd J, Cheung F Analytical and Bioanalytical Chemistry, volume 399, doi:10.1007/s00216-010-4355-7 publication August 2022 Assessment of the exposure to polycyclic aromatic hydrocarbons in users of various tobacco/nicotine products by suitable urinary biomarkers Gerhard Scherer, Max Scherer, Nadine Rögner, Nikola Pluym Archives of Toxicology doi.org/10.1007/s00204-022-03349-4 publication February 2020 Polycyclic aromatic hydrocarbons (PAH) in urine of children and adolescents in Germany - human biomonitoring results of the German Environmental Survey 2014-2017 (GerES V) Murawski A, Roth A, Schwedler G, Schmied-Tobies MIH, Rucic E, Pluym N, Scherer M, Scherer G, Conrad A, Kolossa-Gehring M International Journal of Hygiene and Environmental Health, Volume 226, doi: 10.1016/j.ijheh.2020.113491 publication October 2022 Time trend of exposure to secondhand tobacco smoke and polycyclic aromatic hydrocarbons between 1995 and 2019 in Germany – Showcases for successful European legislation Therese Burkhardt, Max Scherer, Gerhard Scherer, Nikola Pluym, Till Weber, Marike Kolossa-Gehring Environmental Research, doi: 10.1016/j.envres.2022.114638 Conference contribution September 2022 The impact of European legislation on the reduction of Environmental Tobacco Smoke and Polycyclic Aromatic Hydrocarbons between 1995 and 2019 in Germany Therese Burkhardt, Max Scherer, Gerhard Scherer, Till Weber, Nikola Pluym, Marike Kolossa-Gehring ISES 2022, Lisbon
3-Aminobiphenyl (3-ABP)	3-Aminobiphenyl	Urine	GC-MS	publication April 2006 Determination of three carcinogenic aromatic amines in urine of smokers and nonsmokers Riedel K, Scherer G, Engl J, Hagedorn H-W, Tricker AR Journal of Analytical Toxicology, Volume 30, doi: 10.1093/jat/30.3.187 publication November 2022 Assessment of the Exposure to Aromatic Amines in Users of Various Tobacco/Nicotine Products Gerhard Scherer, Kirsten Riedel, Nikola Pluym, Max Scherer ACS Omega, doi: 10.1021/acsomega.2c06130
3-Ethenylpyridine	Tobacco Smoke	Environmental Tobacco Smoke (ETS)	GC-MS
3-Hydroxy-1-methylpropylmercapturic acid (HMPMA)	Crotonaldehyde	Urine	LC-MS/MS	Conference contribution October 2014 Analysis of 18 Urinary Mercapturic Acids by two Multiplex-LC-MS/MS Methods Pluym N, Gilch G, Scherer G, Scherer M CORESTA Congress 2014, Quebec, Canada publication May 2015 Analysis of 18 urinary mercapturic acids by two high-throughput multiplex-LC-MS/MS methods Pluym N, Gilch G, Scherer G, Scherer M Analytical and Bioanalytical Chemistry, Volume 407, doi: 10.1007/s00216-015-8719-x publication June 2021 Assessment of the potential vaping-related exposure to carbonyls and epoxides using stable isotope-labeled precursors in the e-liquid Landmesser A, Scherer M, Scherer G, Sarkar M, Edmiston J, Niessner R, Pluym N Archives of Toxicology, doi:10.1007/s00204-021-03097-x Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients – methods Landmesser A, Pluym N, Scherer G, Sarkar M, Edmiston J, Scherer M CORESTA SSPT 2017, Kitzbühel, Austria Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients–results Landmesser A, Scherer M, Scherer G, Sarkar M, Edmiston J, Pluym N CORESTA SSPT 2017, Kitzbühel, Austria publication October 2022 Comparison of urinary mercapturic acid excretions in users of various tobacco/nicotine products Gerhard Scherer, Nikola Pluym, Max Scherer Drug Testing and Analysis DOI: 10.1002/dta.3372
3-hydroxybenzo[a]pyrene (3-OH-BaP)	Benzo[a]pyrene	Urine	LC-MS/MS	publication October 2021 A Sensitive LC–MS/MS Method for the Quantification of 3-Hydroxybenzo[a]pyrene in Urine-Exposure Assessment in Smokers and Users of Potentially Reduced-Risk Products Rögner N, Hagedorn H-W, Scherer G, Scherer M, Pluym N Separations, 8(10), 171, doi: 10.3390/separations8100171 Conference contribution June 2021 Analysis of 3-hydroxybenzo[a]pyrene in urine as a biomarker of exposure for benzo[a]pyrene in smokers and users of potentially reduced risk products Rögner N, Scherer M, Scherer G, Pluym N Global Forum on Nicotine 2021, Virtual Conference contribution October 2021 Analysis of 3-hydroxybenzo[a]pyrene in urine as a biomarker of exposure for benzo[a]pyrene in smokers and users of potentially reduced risk products Scherer M, Rögner N, Scherer G, Pluym N CORESTA SSPT 2021, Virtual publication October 2022 Time trend of exposure to secondhand tobacco smoke and polycyclic aromatic hydrocarbons between 1995 and 2019 in Germany – Showcases for successful European legislation Therese Burkhardt, Max Scherer, Gerhard Scherer, Nikola Pluym, Till Weber, Marike Kolossa-Gehring Environmental Research, doi: 10.1016/j.envres.2022.114638
3-Hydroxyphenanthrene (3-OH-Phe)	Phenanthrene	Urine	LC-MS/MS	publication November 2010 A liquid chromatography/tandem mass spectrometry (LC-MS/MS) method for the determination of phenolic polycyclic aromatic hydrocarbons (OH-PAH) in urine of non-smokers and smokers Ramsauer B, Sterz K, Hagedorn H-W, Engl J, Scherer G, McEwan M, Errington G, Shepperd J, Cheung F Analytical and Bioanalytical Chemistry, volume 399, doi:10.1007/s00216-010-4355-7 publication August 2022 Assessment of the exposure to polycyclic aromatic hydrocarbons in users of various tobacco/nicotine products by suitable urinary biomarkers Gerhard Scherer, Max Scherer, Nadine Rögner, Nikola Pluym Archives of Toxicology doi.org/10.1007/s00204-022-03349-4 publication February 2020 Polycyclic aromatic hydrocarbons (PAH) in urine of children and adolescents in Germany - human biomonitoring results of the German Environmental Survey 2014-2017 (GerES V) Murawski A, Roth A, Schwedler G, Schmied-Tobies MIH, Rucic E, Pluym N, Scherer M, Scherer G, Conrad A, Kolossa-Gehring M International Journal of Hygiene and Environmental Health, Volume 226, doi: 10.1016/j.ijheh.2020.113491 publication October 2022 Time trend of exposure to secondhand tobacco smoke and polycyclic aromatic hydrocarbons between 1995 and 2019 in Germany – Showcases for successful European legislation Therese Burkhardt, Max Scherer, Gerhard Scherer, Nikola Pluym, Till Weber, Marike Kolossa-Gehring Environmental Research, doi: 10.1016/j.envres.2022.114638 Conference contribution September 2022 The impact of European legislation on the reduction of Environmental Tobacco Smoke and Polycyclic Aromatic Hydrocarbons between 1995 and 2019 in Germany Therese Burkhardt, Max Scherer, Gerhard Scherer, Till Weber, Nikola Pluym, Marike Kolossa-Gehring ISES 2022, Lisbon
3-Hydroxypropylmercapturic acid (3-HPMA)	Acrolein	Urine	LC-MS/MS	Conference contribution October 2014 Analysis of 18 Urinary Mercapturic Acids by two Multiplex-LC-MS/MS Methods Pluym N, Gilch G, Scherer G, Scherer M CORESTA Congress 2014, Quebec, Canada publication May 2015 Analysis of 18 urinary mercapturic acids by two high-throughput multiplex-LC-MS/MS methods Pluym N, Gilch G, Scherer G, Scherer M Analytical and Bioanalytical Chemistry, Volume 407, doi: 10.1007/s00216-015-8719-x Conference contribution October 2019 Analysis of aldehydes, propylene oxide and glycidol in tobacco smoke and e-cigarette vapor and their respective urinary biomarkers Landmesser A, Scherer G, Pluym N, Scherer M CORESTA SSPT 2019, Hamburg, Germany Conference contribution October 2018 Analytical methods for the determination of carbonyls in aerosol from e-vapor products and cigarette smoke and their urinary biomarkers of exposure Landmesser A, Scherer M, Scherer G, Pluym N CORESTA Congress 2018, Kunming, China publication June 2021 Assessment of the potential vaping-related exposure to carbonyls and epoxides using stable isotope-labeled precursors in the e-liquid Landmesser A, Scherer M, Scherer G, Sarkar M, Edmiston J, Niessner R, Pluym N Archives of Toxicology, doi:10.1007/s00204-021-03097-x Conference contribution February 2018 Biomarkers of exposure specific to e-vapor products based on stable-isotope labeled ingredients Landmesser A, Scherer M, Scherer G, Sarkar M, Edmiston J, Pluym N SRNT 2018, Baltimore, USA Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients – methods Landmesser A, Pluym N, Scherer G, Sarkar M, Edmiston J, Scherer M CORESTA SSPT 2017, Kitzbühel, Austria Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients–results Landmesser A, Scherer M, Scherer G, Sarkar M, Edmiston J, Pluym N CORESTA SSPT 2017, Kitzbühel, Austria publication October 2022 Comparison of urinary mercapturic acid excretions in users of various tobacco/nicotine products Gerhard Scherer, Nikola Pluym, Max Scherer Drug Testing and Analysis DOI: 10.1002/dta.3372 Conference contribution October 2018 Novel biomarkers to characterize exposure to aldehydes from e-vapor products based on stable-isotope constituents Landmesser A, Scherer M, Scherer G, Sarkar M, Edmiston J, Pluym N CORESTA Congress 2018, Kunming, China
3-Nitrotyrosine	Nitrosative stress	Plasma	LC-MS/MS
4-Aminobiphenyl (4-ABP)	4-Aminobiphenyl	Urine, ETS	GC-MS	publication April 2014 A correlation study applied to biomarkers of internal and effective dose for acrylonitrile and 4-aminobiphenyl in smokers Scherer G, Newland K, Papadopoulou E, Minet E Biomarkers, Volume 19(4), doi: 10.3109/1354750X.2014.910271 publication April 2006 Determination of three carcinogenic aromatic amines in urine of smokers and nonsmokers Riedel K, Scherer G, Engl J, Hagedorn H-W, Tricker AR Journal of Analytical Toxicology, Volume 30, doi: 10.1093/jat/30.3.187 publication November 2022 Assessment of the Exposure to Aromatic Amines in Users of Various Tobacco/Nicotine Products Gerhard Scherer, Kirsten Riedel, Nikola Pluym, Max Scherer ACS Omega, doi: 10.1021/acsomega.2c06130
4-Hydroxy-4-(3-pyridyl)butanoic acid (HyPyBut)	Nicotine	Urine	LC-MS/MS	Conference contribution October 2013 Assessing the exposure to ‘smoke’ from electronic cigarettes by biomarkers Scherer G, Hagedorn H-W, Riedel K, Scherer M CORESTA SSPT 2013, Seville, Spain publication March 2019 Biomarkers of Exposure Specific to E-vapor Products Based on Stable-Isotope Labeled Ingredients Landmesser A, Scherer M, Pluym N, Sarkar M, Edmiston J, Niessner R, Scherer G Nicotine & Tobacco Research, Volume 21, doi: 10.1093/ntr/nty204 Conference contribution February 2018 Biomarkers of exposure specific to e-vapor products based on stable-isotope labeled ingredients Landmesser A, Scherer M, Scherer G, Sarkar M, Edmiston J, Pluym N SRNT 2018, Baltimore, USA Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients – methods Landmesser A, Pluym N, Scherer G, Sarkar M, Edmiston J, Scherer M CORESTA SSPT 2017, Kitzbühel, Austria Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients–results Landmesser A, Scherer M, Scherer G, Sarkar M, Edmiston J, Pluym N CORESTA SSPT 2017, Kitzbühel, Austria Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients–study design Landmesser A, Pluym N, Scherer G, Sarkar M, Edmiston J, Scherer M CORESTA SSPT 2017, Kitzbühel, Austria publication May 2018 Collaborative Method Performance Study of the Measurement of Nicotine, Its Metabolites, and Total Nicotine Equivalents in Human Urine Wang L, Bernert JT, Benowitz NL, Feng J, Jacob P 3rd, McGahee E, Caudill SP, Scherer G, Scherer M, Pluym N, Doig MV, Newland K, Murphy SE, Caron NJ, Sander LC, Shimizu M, Yamazaki H, Kim S, Langman LJ, Pritchett JS, Sniegoski LT, Li Y, Blount BC, Pirkle JL Cancer Epidemiology, Biomarkers & Prevention, Volume 27, doi: 10.1158/1055-9965 publication January 2014 Simple, fast and sensitive LC-MS/MS analysis for the simultaneous quantification of nicotine and 10 of its major metabolites Piller M, Gilch G, Scherer G, Scherer M Journal of Chromatography B, Volumes 951–952, doi: 10.1016/j.jchromb.2014.01.025 publication March 2022 Assessment of nicotine delivery and uptake in users of various tobacco / nicotine products Scherer G, Mütze J, Pluym N, Scherer M Current Research in Toxicology, Volume 3, 100067
4-Hydroxyphenanthrene (4-OH-Phe)	Phenanthrene	Urine	LC-MS/MS	publication November 2010 A liquid chromatography/tandem mass spectrometry (LC-MS/MS) method for the determination of phenolic polycyclic aromatic hydrocarbons (OH-PAH) in urine of non-smokers and smokers Ramsauer B, Sterz K, Hagedorn H-W, Engl J, Scherer G, McEwan M, Errington G, Shepperd J, Cheung F Analytical and Bioanalytical Chemistry, volume 399, doi:10.1007/s00216-010-4355-7 publication August 2022 Assessment of the exposure to polycyclic aromatic hydrocarbons in users of various tobacco/nicotine products by suitable urinary biomarkers Gerhard Scherer, Max Scherer, Nadine Rögner, Nikola Pluym Archives of Toxicology doi.org/10.1007/s00204-022-03349-4 publication February 2020 Polycyclic aromatic hydrocarbons (PAH) in urine of children and adolescents in Germany - human biomonitoring results of the German Environmental Survey 2014-2017 (GerES V) Murawski A, Roth A, Schwedler G, Schmied-Tobies MIH, Rucic E, Pluym N, Scherer M, Scherer G, Conrad A, Kolossa-Gehring M International Journal of Hygiene and Environmental Health, Volume 226, doi: 10.1016/j.ijheh.2020.113491 publication October 2022 Time trend of exposure to secondhand tobacco smoke and polycyclic aromatic hydrocarbons between 1995 and 2019 in Germany – Showcases for successful European legislation Therese Burkhardt, Max Scherer, Gerhard Scherer, Nikola Pluym, Till Weber, Marike Kolossa-Gehring Environmental Research, doi: 10.1016/j.envres.2022.114638 Conference contribution September 2022 The impact of European legislation on the reduction of Environmental Tobacco Smoke and Polycyclic Aromatic Hydrocarbons between 1995 and 2019 in Germany Therese Burkhardt, Max Scherer, Gerhard Scherer, Till Weber, Nikola Pluym, Marike Kolossa-Gehring ISES 2022, Lisbon
8-Hydroxy-deoxyguanosine (8-OH-dG)	Oxidative stress	Urine	LC-MS/MS	publication October 2018 Identifying suitable biomarkers of biological effects (BOBEs) for evaluating reduced risk products Scherer G, Pluym N, Scherer M CORESTA Congress 2018, Biomarker Workshop, Kunming, China publication October 2017 Metabolomic Fingerprinting in Various Body Fluids of a Diet-Controlled Clinical Smoking Cessation Study Using a Validated GC-TOF-MS Metabolomics Platform Goettel M, Niessner R, Mueller D, Scherer M, Scherer G, Pluym N Journal of Proteome Research, Volume 16(10), doi: 10.1021/acs.jproteome.7b00128. publication April 2018 Suitability of biomarkers of biological effects (BOBEs) for assessing the likelihood of reducing the tobacco related disease risk by new and innovative tobacco products: A literature review Scherer G Regulatory Toxicology and Pharmacology, Volume 94, doi: 10.1016/j.yrtph.2018.02.002
8-iso-PGF2α	Oxidative Stress	Urine	LC-MS/MS	publication February 2012 A simple and robust UPLC-SRM/MS method to quantify urinary eicosanoids Sterz K, Scherer G, Ecker J Journal of Lipid Research, Volume 53, doi: 10.1194/jlr.D023739 publication March 2018 Analysis of Urinary Eicosanoids by LC-MS/MS Reveals Alterations in the Metabolic Profile after Smoking Cessation Goettel M, Niessner R, Scherer M, Scherer G, Pluym N Chemical Research in Toxicology, Volume 31, doi: 10.1021/acs.chemrestox publication October 2018 Identifying suitable biomarkers of biological effects (BOBEs) for evaluating reduced risk products Scherer G, Pluym N, Scherer M CORESTA Congress 2018, Biomarker Workshop, Kunming, China publication October 2017 Metabolomic Fingerprinting in Various Body Fluids of a Diet-Controlled Clinical Smoking Cessation Study Using a Validated GC-TOF-MS Metabolomics Platform Goettel M, Niessner R, Mueller D, Scherer M, Scherer G, Pluym N Journal of Proteome Research, Volume 16(10), doi: 10.1021/acs.jproteome.7b00128. publication January 2018 Review of biomarkers to assess the effects of switching from cigarettes to modified risk tobacco products Peck MJ, Sanders EB, Scherer G, Luedicke F, Weitkunat R Biomarkers, Volume 23(3), doi: 10.1080/1354750X.2017.1419284 publication April 2018 Suitability of biomarkers of biological effects (BOBEs) for assessing the likelihood of reducing the tobacco related disease risk by new and innovative tobacco products: A literature review Scherer G Regulatory Toxicology and Pharmacology, Volume 94, doi: 10.1016/j.yrtph.2018.02.002
9-Hydroxyphenanthrene (9-OH-Phe)	Phenanthrene	Urine	LC-MS/MS	publication November 2010 A liquid chromatography/tandem mass spectrometry (LC-MS/MS) method for the determination of phenolic polycyclic aromatic hydrocarbons (OH-PAH) in urine of non-smokers and smokers Ramsauer B, Sterz K, Hagedorn H-W, Engl J, Scherer G, McEwan M, Errington G, Shepperd J, Cheung F Analytical and Bioanalytical Chemistry, volume 399, doi:10.1007/s00216-010-4355-7 publication August 2022 Assessment of the exposure to polycyclic aromatic hydrocarbons in users of various tobacco/nicotine products by suitable urinary biomarkers Gerhard Scherer, Max Scherer, Nadine Rögner, Nikola Pluym Archives of Toxicology doi.org/10.1007/s00204-022-03349-4 publication February 2020 Polycyclic aromatic hydrocarbons (PAH) in urine of children and adolescents in Germany - human biomonitoring results of the German Environmental Survey 2014-2017 (GerES V) Murawski A, Roth A, Schwedler G, Schmied-Tobies MIH, Rucic E, Pluym N, Scherer M, Scherer G, Conrad A, Kolossa-Gehring M International Journal of Hygiene and Environmental Health, Volume 226, doi: 10.1016/j.ijheh.2020.113491 publication October 2022 Time trend of exposure to secondhand tobacco smoke and polycyclic aromatic hydrocarbons between 1995 and 2019 in Germany – Showcases for successful European legislation Therese Burkhardt, Max Scherer, Gerhard Scherer, Nikola Pluym, Till Weber, Marike Kolossa-Gehring Environmental Research, doi: 10.1016/j.envres.2022.114638 Conference contribution September 2022 The impact of European legislation on the reduction of Environmental Tobacco Smoke and Polycyclic Aromatic Hydrocarbons between 1995 and 2019 in Germany Therese Burkhardt, Max Scherer, Gerhard Scherer, Till Weber, Nikola Pluym, Marike Kolossa-Gehring ISES 2022, Lisbon
Acetaldehyde (FA)	Tobacco Smoke, E-Vapor Aerosol	ETS, e-liquids, aerosol	LC-MS/MS
Acetone	Tobacco Smoke, E-Vapor Aerosol	ETS, e-liquids, aerosol	LC-MS/MS
Acrolein (ACR)	Tobacco Smoke, E-Vapor Aerosol	ETS, e-liquids, aerosol	LC-MS/MS
Acrylamidemercapturic acid (AAMA)	Acrylamide	Urine	LC-MS/MS	Conference contribution October 2014 Analysis of 18 Urinary Mercapturic Acids by two Multiplex-LC-MS/MS Methods Pluym N, Gilch G, Scherer G, Scherer M CORESTA Congress 2014, Quebec, Canada publication May 2015 Analysis of 18 urinary mercapturic acids by two high-throughput multiplex-LC-MS/MS methods Pluym N, Gilch G, Scherer G, Scherer M Analytical and Bioanalytical Chemistry, Volume 407, doi: 10.1007/s00216-015-8719-x publication October 2020 Benzene metabolite SPMA and acrylamide metabolites AAMA and GAMA in urine of children and adolescents in Germany - human biomonitoring results of the German Environmental Survey 2014-2017 (GerES V) Schwedler G, Murawski A, Schmied-Tobies MIH, Rucic E, Scherer M, Pluym N, Scherer G, Bethke R, Kolossa-Gehring M Environmental Research, Volume 192, doi: 10.1016/j.envres.2020.110295 publication October 2022 Comparison of urinary mercapturic acid excretions in users of various tobacco/nicotine products Gerhard Scherer, Nikola Pluym, Max Scherer Drug Testing and Analysis DOI: 10.1002/dta.3372 publication March 2006 Urinary Mercapturic Acids and a Hemoglobin Adduct for the Dosimetry of Acrylamide Exposure in Smokers and Nonsmokers Urban M, Kavvadias D, Riedel K, Scherer G, Tricker AR Inhalation Toxicology, Volume 18, doi: 10.1080/08958370600748430
Anabasine (AB)	Anabasine	Plasma, Urine	LC-MS/MS
Anatabine (AT)	Anatabine	Plasma, Urine	LC-MS/MS
Benzene	Tobacco Smoke	ETS	GC-MS
Benzo[a]pyrene (BaP)	PAH	ETS	GC-MS
Benzo[a]pyrene tetrol (BaP-tetrol)	Benzo[a]pyrene	Urine	GC-MS/MS	Conference contribution October 2024 A sensitive GC–MS/MS method for the quantification of benzo[a]pyrene tetrol in urine Max Scherer, Fabian Pilz, Antonia Gärtner, Gerhard Scherer, Nikola Pluym CORESTA Congress 2024, Edinburgh, UK publication March 2024 A sensitive GC–MS/MS method for the quantification of benzo[a]pyrene tetrol in urine Fabian Pilz, Antonia Gärtner, Nikola Pluym, Gerhard Scherer, Max Scherer Analytical and Bioanalytical Chemistry
Citronellol	Flavor	Urine	HS-SPME-GC-MS
Cotinine	Nicotine	Urine, Plasma, Serum, Saliva	LC-MS/MS	Conference contribution October 2013 Assessing the exposure to ‘smoke’ from electronic cigarettes by biomarkers Scherer G, Hagedorn H-W, Riedel K, Scherer M CORESTA SSPT 2013, Seville, Spain publication March 2019 Biomarkers of Exposure Specific to E-vapor Products Based on Stable-Isotope Labeled Ingredients Landmesser A, Scherer M, Pluym N, Sarkar M, Edmiston J, Niessner R, Scherer G Nicotine & Tobacco Research, Volume 21, doi: 10.1093/ntr/nty204 Conference contribution February 2018 Biomarkers of exposure specific to e-vapor products based on stable-isotope labeled ingredients Landmesser A, Scherer M, Scherer G, Sarkar M, Edmiston J, Pluym N SRNT 2018, Baltimore, USA Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients – methods Landmesser A, Pluym N, Scherer G, Sarkar M, Edmiston J, Scherer M CORESTA SSPT 2017, Kitzbühel, Austria Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients–results Landmesser A, Scherer M, Scherer G, Sarkar M, Edmiston J, Pluym N CORESTA SSPT 2017, Kitzbühel, Austria Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients–study design Landmesser A, Pluym N, Scherer G, Sarkar M, Edmiston J, Scherer M CORESTA SSPT 2017, Kitzbühel, Austria publication May 2018 Collaborative Method Performance Study of the Measurement of Nicotine, Its Metabolites, and Total Nicotine Equivalents in Human Urine Wang L, Bernert JT, Benowitz NL, Feng J, Jacob P 3rd, McGahee E, Caudill SP, Scherer G, Scherer M, Pluym N, Doig MV, Newland K, Murphy SE, Caron NJ, Sander LC, Shimizu M, Yamazaki H, Kim S, Langman LJ, Pritchett JS, Sniegoski LT, Li Y, Blount BC, Pirkle JL Cancer Epidemiology, Biomarkers & Prevention, Volume 27, doi: 10.1158/1055-9965 publication March 2014 Saliva as a matrix for human biomonitoring in occupational and environmental medicine Michalke B, Rossbach B, Göen T, Schäferhenrich A, Scherer G International Archives of Occupational and Environmental Health, volume 88, doi: 10.1007/s00420-014-0938-5 publication January 2014 Simple, fast and sensitive LC-MS/MS analysis for the simultaneous quantification of nicotine and 10 of its major metabolites Piller M, Gilch G, Scherer G, Scherer M Journal of Chromatography B, Volumes 951–952, doi: 10.1016/j.jchromb.2014.01.025 publication October 2022 Time trend of exposure to secondhand tobacco smoke and polycyclic aromatic hydrocarbons between 1995 and 2019 in Germany – Showcases for successful European legislation Therese Burkhardt, Max Scherer, Gerhard Scherer, Nikola Pluym, Till Weber, Marike Kolossa-Gehring Environmental Research, doi: 10.1016/j.envres.2022.114638
Cotinine-glucuronide	Nicotine	Urine	LC-MS/MS	Conference contribution October 2013 Assessing the exposure to ‘smoke’ from electronic cigarettes by biomarkers Scherer G, Hagedorn H-W, Riedel K, Scherer M CORESTA SSPT 2013, Seville, Spain publication March 2019 Biomarkers of Exposure Specific to E-vapor Products Based on Stable-Isotope Labeled Ingredients Landmesser A, Scherer M, Pluym N, Sarkar M, Edmiston J, Niessner R, Scherer G Nicotine & Tobacco Research, Volume 21, doi: 10.1093/ntr/nty204 Conference contribution February 2018 Biomarkers of exposure specific to e-vapor products based on stable-isotope labeled ingredients Landmesser A, Scherer M, Scherer G, Sarkar M, Edmiston J, Pluym N SRNT 2018, Baltimore, USA Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients – methods Landmesser A, Pluym N, Scherer G, Sarkar M, Edmiston J, Scherer M CORESTA SSPT 2017, Kitzbühel, Austria Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients–results Landmesser A, Scherer M, Scherer G, Sarkar M, Edmiston J, Pluym N CORESTA SSPT 2017, Kitzbühel, Austria Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients–study design Landmesser A, Pluym N, Scherer G, Sarkar M, Edmiston J, Scherer M CORESTA SSPT 2017, Kitzbühel, Austria publication May 2018 Collaborative Method Performance Study of the Measurement of Nicotine, Its Metabolites, and Total Nicotine Equivalents in Human Urine Wang L, Bernert JT, Benowitz NL, Feng J, Jacob P 3rd, McGahee E, Caudill SP, Scherer G, Scherer M, Pluym N, Doig MV, Newland K, Murphy SE, Caron NJ, Sander LC, Shimizu M, Yamazaki H, Kim S, Langman LJ, Pritchett JS, Sniegoski LT, Li Y, Blount BC, Pirkle JL Cancer Epidemiology, Biomarkers & Prevention, Volume 27, doi: 10.1158/1055-9965 publication January 2014 Simple, fast and sensitive LC-MS/MS analysis for the simultaneous quantification of nicotine and 10 of its major metabolites Piller M, Gilch G, Scherer G, Scherer M Journal of Chromatography B, Volumes 951–952, doi: 10.1016/j.jchromb.2014.01.025 publication March 2022 Assessment of nicotine delivery and uptake in users of various tobacco / nicotine products Scherer G, Mütze J, Pluym N, Scherer M Current Research in Toxicology, Volume 3, 100067
Cotinine-N-oxide (CNO)	Nicotine	Urine	LC-MS/MS	Conference contribution October 2013 Assessing the exposure to ‘smoke’ from electronic cigarettes by biomarkers Scherer G, Hagedorn H-W, Riedel K, Scherer M CORESTA SSPT 2013, Seville, Spain publication March 2019 Biomarkers of Exposure Specific to E-vapor Products Based on Stable-Isotope Labeled Ingredients Landmesser A, Scherer M, Pluym N, Sarkar M, Edmiston J, Niessner R, Scherer G Nicotine & Tobacco Research, Volume 21, doi: 10.1093/ntr/nty204 Conference contribution February 2018 Biomarkers of exposure specific to e-vapor products based on stable-isotope labeled ingredients Landmesser A, Scherer M, Scherer G, Sarkar M, Edmiston J, Pluym N SRNT 2018, Baltimore, USA Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients – methods Landmesser A, Pluym N, Scherer G, Sarkar M, Edmiston J, Scherer M CORESTA SSPT 2017, Kitzbühel, Austria Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients–results Landmesser A, Scherer M, Scherer G, Sarkar M, Edmiston J, Pluym N CORESTA SSPT 2017, Kitzbühel, Austria Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients–study design Landmesser A, Pluym N, Scherer G, Sarkar M, Edmiston J, Scherer M CORESTA SSPT 2017, Kitzbühel, Austria publication May 2018 Collaborative Method Performance Study of the Measurement of Nicotine, Its Metabolites, and Total Nicotine Equivalents in Human Urine Wang L, Bernert JT, Benowitz NL, Feng J, Jacob P 3rd, McGahee E, Caudill SP, Scherer G, Scherer M, Pluym N, Doig MV, Newland K, Murphy SE, Caron NJ, Sander LC, Shimizu M, Yamazaki H, Kim S, Langman LJ, Pritchett JS, Sniegoski LT, Li Y, Blount BC, Pirkle JL Cancer Epidemiology, Biomarkers & Prevention, Volume 27, doi: 10.1158/1055-9965 publication January 2014 Simple, fast and sensitive LC-MS/MS analysis for the simultaneous quantification of nicotine and 10 of its major metabolites Piller M, Gilch G, Scherer G, Scherer M Journal of Chromatography B, Volumes 951–952, doi: 10.1016/j.jchromb.2014.01.025 publication March 2022 Assessment of nicotine delivery and uptake in users of various tobacco / nicotine products Scherer G, Mütze J, Pluym N, Scherer M Current Research in Toxicology, Volume 3, 100067
Creatinine	Normalization of urinary biomarker concentrations	Urine	Photometry
Cyanoethylmercapturic acid (CEMA)	Acrylonitrile	Urine	LC-MS/MS	publication April 2014 A correlation study applied to biomarkers of internal and effective dose for acrylonitrile and 4-aminobiphenyl in smokers Scherer G, Newland K, Papadopoulou E, Minet E Biomarkers, Volume 19(4), doi: 10.3109/1354750X.2014.910271 Conference contribution October 2014 Analysis of 18 Urinary Mercapturic Acids by two Multiplex-LC-MS/MS Methods Pluym N, Gilch G, Scherer G, Scherer M CORESTA Congress 2014, Quebec, Canada publication May 2015 Analysis of 18 urinary mercapturic acids by two high-throughput multiplex-LC-MS/MS methods Pluym N, Gilch G, Scherer G, Scherer M Analytical and Bioanalytical Chemistry, Volume 407, doi: 10.1007/s00216-015-8719-x publication October 2022 Comparison of urinary mercapturic acid excretions in users of various tobacco/nicotine products Gerhard Scherer, Nikola Pluym, Max Scherer Drug Testing and Analysis DOI: 10.1002/dta.3372
DHN-MA	Oxidative stress, Lipid peroxidation	Urine	LC-MS/MS
Dihydroxybutenylmercapturic acid (DHBMA)	1,3-Butadiene	Urine	LC-MS/MS	Conference contribution October 2014 Analysis of 18 Urinary Mercapturic Acids by two Multiplex-LC-MS/MS Methods Pluym N, Gilch G, Scherer G, Scherer M CORESTA Congress 2014, Quebec, Canada publication May 2015 Analysis of 18 urinary mercapturic acids by two high-throughput multiplex-LC-MS/MS methods Pluym N, Gilch G, Scherer G, Scherer M Analytical and Bioanalytical Chemistry, Volume 407, doi: 10.1007/s00216-015-8719-x publication October 2022 Comparison of urinary mercapturic acid excretions in users of various tobacco/nicotine products Gerhard Scherer, Nikola Pluym, Max Scherer Drug Testing and Analysis DOI: 10.1002/dta.3372
Dihydroxypropylmercapturic acid (DHPMA)	Glycidol	Urine	LC-MS/MS	Conference contribution October 2019 Analysis of aldehydes, propylene oxide and glycidol in tobacco smoke and e-cigarette vapor and their respective urinary biomarkers Landmesser A, Scherer G, Pluym N, Scherer M CORESTA SSPT 2019, Hamburg, Germany Conference contribution October 2018 Analytical methods for the determination of carbonyls in aerosol from e-vapor products and cigarette smoke and their urinary biomarkers of exposure Landmesser A, Scherer M, Scherer G, Pluym N CORESTA Congress 2018, Kunming, China publication June 2021 Assessment of the potential vaping-related exposure to carbonyls and epoxides using stable isotope-labeled precursors in the e-liquid Landmesser A, Scherer M, Scherer G, Sarkar M, Edmiston J, Niessner R, Pluym N Archives of Toxicology, doi:10.1007/s00204-021-03097-x Conference contribution February 2018 Biomarkers of exposure specific to e-vapor products based on stable-isotope labeled ingredients Landmesser A, Scherer M, Scherer G, Sarkar M, Edmiston J, Pluym N SRNT 2018, Baltimore, USA Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients – methods Landmesser A, Pluym N, Scherer G, Sarkar M, Edmiston J, Scherer M CORESTA SSPT 2017, Kitzbühel, Austria Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients–results Landmesser A, Scherer M, Scherer G, Sarkar M, Edmiston J, Pluym N CORESTA SSPT 2017, Kitzbühel, Austria publication October 2022 Comparison of urinary mercapturic acid excretions in users of various tobacco/nicotine products Gerhard Scherer, Nikola Pluym, Max Scherer Drug Testing and Analysis DOI: 10.1002/dta.3372 Conference contribution October 2018 Novel biomarkers to characterize exposure to aldehydes from e-vapor products based on stable-isotope constituents Landmesser A, Scherer M, Scherer G, Sarkar M, Edmiston J, Pluym N CORESTA Congress 2018, Kunming, China Conference contribution February 2019 Novel biomarkers to characterize the specific exposure to aldehydes or epoxides from e-vapor products based on stable-isotope labeled constituents Landmesser A, Scherer M, Scherer G, Pluym N SRNT 2019, San Francisco, USA
Eugenol	Flavor	Urine	HS-SPME-GC-MS
F-PM	Tobacco Smoke	Environmental Tobacco Smoke (ETS)	Fluorescence
Fromaldehyde (FA)	Tobacco Smoke, E-Vapor, Aerosol	ETS, e-liquids, aerosol	LC-MS/MS
Glycerol	Glycerol	Urine, Plasma, Serum, Saliva, PBS, ETS, Aerosol, e-liquids	LC-MS/MS	publication March 2019 Biomarkers of Exposure Specific to E-vapor Products Based on Stable-Isotope Labeled Ingredients Landmesser A, Scherer M, Pluym N, Sarkar M, Edmiston J, Niessner R, Scherer G Nicotine & Tobacco Research, Volume 21, doi: 10.1093/ntr/nty204 Conference contribution February 2018 Biomarkers of exposure specific to e-vapor products based on stable-isotope labeled ingredients Landmesser A, Scherer M, Scherer G, Sarkar M, Edmiston J, Pluym N SRNT 2018, Baltimore, USA Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients – methods Landmesser A, Pluym N, Scherer G, Sarkar M, Edmiston J, Scherer M CORESTA SSPT 2017, Kitzbühel, Austria Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients–results Landmesser A, Scherer M, Scherer G, Sarkar M, Edmiston J, Pluym N CORESTA SSPT 2017, Kitzbühel, Austria Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients–study design Landmesser A, Pluym N, Scherer G, Sarkar M, Edmiston J, Scherer M CORESTA SSPT 2017, Kitzbühel, Austria Conference contribution October 2013 Assessing the exposure to ‘smoke’ from electronic cigarettes by biomarkers Scherer G, Hagedorn H-W, Riedel K, Scherer M CORESTA SSPT 2013, Seville, Spain
Glycidamidemercapturic acid (GAMA)	Acrylamide	Urine	LC-MS/MS	Conference contribution October 2014 Analysis of 18 Urinary Mercapturic Acids by two Multiplex-LC-MS/MS Methods Pluym N, Gilch G, Scherer G, Scherer M CORESTA Congress 2014, Quebec, Canada publication May 2015 Analysis of 18 urinary mercapturic acids by two high-throughput multiplex-LC-MS/MS methods Pluym N, Gilch G, Scherer G, Scherer M Analytical and Bioanalytical Chemistry, Volume 407, doi: 10.1007/s00216-015-8719-x publication October 2020 Benzene metabolite SPMA and acrylamide metabolites AAMA and GAMA in urine of children and adolescents in Germany - human biomonitoring results of the German Environmental Survey 2014-2017 (GerES V) Schwedler G, Murawski A, Schmied-Tobies MIH, Rucic E, Scherer M, Pluym N, Scherer G, Bethke R, Kolossa-Gehring M Environmental Research, Volume 192, doi: 10.1016/j.envres.2020.110295 publication October 2022 Comparison of urinary mercapturic acid excretions in users of various tobacco/nicotine products Gerhard Scherer, Nikola Pluym, Max Scherer Drug Testing and Analysis DOI: 10.1002/dta.3372 publication March 2006 Urinary Mercapturic Acids and a Hemoglobin Adduct for the Dosimetry of Acrylamide Exposure in Smokers and Nonsmokers Urban M, Kavvadias D, Riedel K, Scherer G, Tricker AR Inhalation Toxicology, Volume 18, doi: 10.1080/08958370600748430
HNA-Lactone-MA	Oxidative stress, Lipid peroxidation	Urine	LC-MS/MS
HNA-MA	Oxidative stress, Lipid peroxidation	Urine	LC-MS/MS
HNE-MA	Oxidative stress, Lipid peroxidation	Urine	LC-MS/MS
Homocysteine	Amino acid metabolism	Plasma	LC-MS/MS
Isoprenemercapturic acid (IPMA-3)	Isoprene	Urine	LC-MS/MS
L-Carvone	Flavor	Urine	HS-SPME-GC-MS
Leukotriene E4	Inflammation	Urine	LC-MS/MS	publication February 2012 A simple and robust UPLC-SRM/MS method to quantify urinary eicosanoids Sterz K, Scherer G, Ecker J Journal of Lipid Research, Volume 53, doi: 10.1194/jlr.D023739 publication March 2018 Analysis of Urinary Eicosanoids by LC-MS/MS Reveals Alterations in the Metabolic Profile after Smoking Cessation Goettel M, Niessner R, Scherer M, Scherer G, Pluym N Chemical Research in Toxicology, Volume 31, doi: 10.1021/acs.chemrestox publication October 2017 Metabolomic Fingerprinting in Various Body Fluids of a Diet-Controlled Clinical Smoking Cessation Study Using a Validated GC-TOF-MS Metabolomics Platform Goettel M, Niessner R, Mueller D, Scherer M, Scherer G, Pluym N Journal of Proteome Research, Volume 16(10), doi: 10.1021/acs.jproteome.7b00128. publication April 2018 Suitability of biomarkers of biological effects (BOBEs) for assessing the likelihood of reducing the tobacco related disease risk by new and innovative tobacco products: A literature review Scherer G Regulatory Toxicology and Pharmacology, Volume 94, doi: 10.1016/j.yrtph.2018.02.002
Linalool	Flavor	Urine	HS-SPME-GC-MS
MDA	Oxidative stress, lipid peroxidation	Plasma, Exhaled Breath	GC-MS	publication October 2018 Identifying suitable biomarkers of biological effects (BOBEs) for evaluating reduced risk products Scherer G, Pluym N, Scherer M CORESTA Congress 2018, Biomarker Workshop, Kunming, China publication October 2017 Metabolomic Fingerprinting in Various Body Fluids of a Diet-Controlled Clinical Smoking Cessation Study Using a Validated GC-TOF-MS Metabolomics Platform Goettel M, Niessner R, Mueller D, Scherer M, Scherer G, Pluym N Journal of Proteome Research, Volume 16(10), doi: 10.1021/acs.jproteome.7b00128. publication April 2018 Suitability of biomarkers of biological effects (BOBEs) for assessing the likelihood of reducing the tobacco related disease risk by new and innovative tobacco products: A literature review Scherer G Regulatory Toxicology and Pharmacology, Volume 94, doi: 10.1016/j.yrtph.2018.02.002
Menthol	Flavor	Urine	HS-SPME-GC-MS
Methacrolein	Tobacco Smoke, E-Vapor Aerosol	ETS, e-liquids, aerosol	LC-MS/MS
Monohydroxybutenylmercapturic acid 1 (1-MHBMA)	1,3-Butadiene	Urine	LC-MS/MS	Conference contribution October 2014 Analysis of 18 Urinary Mercapturic Acids by two Multiplex-LC-MS/MS Methods Pluym N, Gilch G, Scherer G, Scherer M CORESTA Congress 2014, Quebec, Canada publication May 2015 Analysis of 18 urinary mercapturic acids by two high-throughput multiplex-LC-MS/MS methods Pluym N, Gilch G, Scherer G, Scherer M Analytical and Bioanalytical Chemistry, Volume 407, doi: 10.1007/s00216-015-8719-x publication October 2022 Comparison of urinary mercapturic acid excretions in users of various tobacco/nicotine products Gerhard Scherer, Nikola Pluym, Max Scherer Drug Testing and Analysis DOI: 10.1002/dta.3372
Monohydroxybutenylmercapturic acid 2 (2-MHBMA)	1,3-Butadiene	Urine	LC-MS/MS	Conference contribution October 2014 Analysis of 18 Urinary Mercapturic Acids by two Multiplex-LC-MS/MS Methods Pluym N, Gilch G, Scherer G, Scherer M CORESTA Congress 2014, Quebec, Canada publication May 2015 Analysis of 18 urinary mercapturic acids by two high-throughput multiplex-LC-MS/MS methods Pluym N, Gilch G, Scherer G, Scherer M Analytical and Bioanalytical Chemistry, Volume 407, doi: 10.1007/s00216-015-8719-x publication October 2022 Comparison of urinary mercapturic acid excretions in users of various tobacco/nicotine products Gerhard Scherer, Nikola Pluym, Max Scherer Drug Testing and Analysis DOI: 10.1002/dta.3372
Nicotine-glucuronide (Nic-gluc)	Nicotine	Urine	LC-MS/MS	Conference contribution October 2013 Assessing the exposure to ‘smoke’ from electronic cigarettes by biomarkers Scherer G, Hagedorn H-W, Riedel K, Scherer M CORESTA SSPT 2013, Seville, Spain publication March 2019 Biomarkers of Exposure Specific to E-vapor Products Based on Stable-Isotope Labeled Ingredients Landmesser A, Scherer M, Pluym N, Sarkar M, Edmiston J, Niessner R, Scherer G Nicotine & Tobacco Research, Volume 21, doi: 10.1093/ntr/nty204 Conference contribution February 2018 Biomarkers of exposure specific to e-vapor products based on stable-isotope labeled ingredients Landmesser A, Scherer M, Scherer G, Sarkar M, Edmiston J, Pluym N SRNT 2018, Baltimore, USA Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients – methods Landmesser A, Pluym N, Scherer G, Sarkar M, Edmiston J, Scherer M CORESTA SSPT 2017, Kitzbühel, Austria Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients–results Landmesser A, Scherer M, Scherer G, Sarkar M, Edmiston J, Pluym N CORESTA SSPT 2017, Kitzbühel, Austria Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients–study design Landmesser A, Pluym N, Scherer G, Sarkar M, Edmiston J, Scherer M CORESTA SSPT 2017, Kitzbühel, Austria publication May 2018 Collaborative Method Performance Study of the Measurement of Nicotine, Its Metabolites, and Total Nicotine Equivalents in Human Urine Wang L, Bernert JT, Benowitz NL, Feng J, Jacob P 3rd, McGahee E, Caudill SP, Scherer G, Scherer M, Pluym N, Doig MV, Newland K, Murphy SE, Caron NJ, Sander LC, Shimizu M, Yamazaki H, Kim S, Langman LJ, Pritchett JS, Sniegoski LT, Li Y, Blount BC, Pirkle JL Cancer Epidemiology, Biomarkers & Prevention, Volume 27, doi: 10.1158/1055-9965 publication January 2014 Simple, fast and sensitive LC-MS/MS analysis for the simultaneous quantification of nicotine and 10 of its major metabolites Piller M, Gilch G, Scherer G, Scherer M Journal of Chromatography B, Volumes 951–952, doi: 10.1016/j.jchromb.2014.01.025 publication March 2022 Assessment of nicotine delivery and uptake in users of various tobacco / nicotine products Scherer G, Mütze J, Pluym N, Scherer M Current Research in Toxicology, Volume 3, 100067
Nicotine (Nic)	Nicotine	Urine, Plasma, Serum, Saliva, PBS, ETS, e-liquids, aerosol	LC-MS/MS, GC-MS	Conference contribution October 2013 Assessing the exposure to ‘smoke’ from electronic cigarettes by biomarkers Scherer G, Hagedorn H-W, Riedel K, Scherer M CORESTA SSPT 2013, Seville, Spain publication March 2019 Biomarkers of Exposure Specific to E-vapor Products Based on Stable-Isotope Labeled Ingredients Landmesser A, Scherer M, Pluym N, Sarkar M, Edmiston J, Niessner R, Scherer G Nicotine & Tobacco Research, Volume 21, doi: 10.1093/ntr/nty204 Conference contribution February 2018 Biomarkers of exposure specific to e-vapor products based on stable-isotope labeled ingredients Landmesser A, Scherer M, Scherer G, Sarkar M, Edmiston J, Pluym N SRNT 2018, Baltimore, USA Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients – methods Landmesser A, Pluym N, Scherer G, Sarkar M, Edmiston J, Scherer M CORESTA SSPT 2017, Kitzbühel, Austria Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients–results Landmesser A, Scherer M, Scherer G, Sarkar M, Edmiston J, Pluym N CORESTA SSPT 2017, Kitzbühel, Austria Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients–study design Landmesser A, Pluym N, Scherer G, Sarkar M, Edmiston J, Scherer M CORESTA SSPT 2017, Kitzbühel, Austria publication May 2018 Collaborative Method Performance Study of the Measurement of Nicotine, Its Metabolites, and Total Nicotine Equivalents in Human Urine Wang L, Bernert JT, Benowitz NL, Feng J, Jacob P 3rd, McGahee E, Caudill SP, Scherer G, Scherer M, Pluym N, Doig MV, Newland K, Murphy SE, Caron NJ, Sander LC, Shimizu M, Yamazaki H, Kim S, Langman LJ, Pritchett JS, Sniegoski LT, Li Y, Blount BC, Pirkle JL Cancer Epidemiology, Biomarkers & Prevention, Volume 27, doi: 10.1158/1055-9965 publication March 2014 Saliva as a matrix for human biomonitoring in occupational and environmental medicine Michalke B, Rossbach B, Göen T, Schäferhenrich A, Scherer G International Archives of Occupational and Environmental Health, volume 88, doi: 10.1007/s00420-014-0938-5 publication January 2014 Simple, fast and sensitive LC-MS/MS analysis for the simultaneous quantification of nicotine and 10 of its major metabolites Piller M, Gilch G, Scherer G, Scherer M Journal of Chromatography B, Volumes 951–952, doi: 10.1016/j.jchromb.2014.01.025 Conference contribution October 2016 Ultra-sensitive method for the determination of nicotine in PK studies with next generation products Wanderer F, Pluym N, Scherer G, Scherer M CORESTA Congress 2016, Berlin, Germany
Nicotine-N-oxide (NNO)	Nicotine	Urine	LC-MS/MS	Conference contribution October 2013 Assessing the exposure to ‘smoke’ from electronic cigarettes by biomarkers Scherer G, Hagedorn H-W, Riedel K, Scherer M CORESTA SSPT 2013, Seville, Spain publication March 2019 Biomarkers of Exposure Specific to E-vapor Products Based on Stable-Isotope Labeled Ingredients Landmesser A, Scherer M, Pluym N, Sarkar M, Edmiston J, Niessner R, Scherer G Nicotine & Tobacco Research, Volume 21, doi: 10.1093/ntr/nty204 Conference contribution February 2018 Biomarkers of exposure specific to e-vapor products based on stable-isotope labeled ingredients Landmesser A, Scherer M, Scherer G, Sarkar M, Edmiston J, Pluym N SRNT 2018, Baltimore, USA Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients – methods Landmesser A, Pluym N, Scherer G, Sarkar M, Edmiston J, Scherer M CORESTA SSPT 2017, Kitzbühel, Austria Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients–results Landmesser A, Scherer M, Scherer G, Sarkar M, Edmiston J, Pluym N CORESTA SSPT 2017, Kitzbühel, Austria Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients–study design Landmesser A, Pluym N, Scherer G, Sarkar M, Edmiston J, Scherer M CORESTA SSPT 2017, Kitzbühel, Austria publication May 2018 Collaborative Method Performance Study of the Measurement of Nicotine, Its Metabolites, and Total Nicotine Equivalents in Human Urine Wang L, Bernert JT, Benowitz NL, Feng J, Jacob P 3rd, McGahee E, Caudill SP, Scherer G, Scherer M, Pluym N, Doig MV, Newland K, Murphy SE, Caron NJ, Sander LC, Shimizu M, Yamazaki H, Kim S, Langman LJ, Pritchett JS, Sniegoski LT, Li Y, Blount BC, Pirkle JL Cancer Epidemiology, Biomarkers & Prevention, Volume 27, doi: 10.1158/1055-9965 publication January 2014 Simple, fast and sensitive LC-MS/MS analysis for the simultaneous quantification of nicotine and 10 of its major metabolites Piller M, Gilch G, Scherer G, Scherer M Journal of Chromatography B, Volumes 951–952, doi: 10.1016/j.jchromb.2014.01.025 publication March 2022 Assessment of nicotine delivery and uptake in users of various tobacco / nicotine products Scherer G, Mütze J, Pluym N, Scherer M Current Research in Toxicology, Volume 3, 100067
NNAL	NNK (Nicotine-derived nitrosamine ketone)	Urine	LC-MS/MS	publication March 2022 Assessment of the Exposure to Tobacco-Specific Nitrosamines and Minor Tobacco Alkaloids in Users of Various Tobacco/Nicotine Products Scherer G, Scherer M, Mütze J, Hauke T, Pluym N Chemical Research in Toxicology, doi: 10.1021/acs.chemrestox.2c00020 publication December 2009 Determination of tobacco-specific N-nitrosamines in urine of smokers and non-smokers Kavvadias D, Scherer G, Cheung F, Errington G, Shepperd J, McEwan M Biomarkers, Volume 14, doi: 10.3109/13547500903242883 publication January 2018 Review of biomarkers to assess the effects of switching from cigarettes to modified risk tobacco products Peck MJ, Sanders EB, Scherer G, Luedicke F, Weitkunat R Biomarkers, Volume 23(3), doi: 10.1080/1354750X.2017.1419284 publication March 2009 Simultaneous determination of four tobacco-specific N-nitrosamines (TSNA) in human urine Kavvadias D, Scherer G, Urban M, Cheung F, Errington G, Shepperd J, McEwan M Journal of Chromatography B, Volume 877, doi: 10.1016/j.jchromb.2009.03.009
N-Nitrosoanabasine (NAB)	NAB	Urine, ETS, Aerosol	LC-MS/MS, GC-MS	publication March 2022 Assessment of the Exposure to Tobacco-Specific Nitrosamines and Minor Tobacco Alkaloids in Users of Various Tobacco/Nicotine Products Scherer G, Scherer M, Mütze J, Hauke T, Pluym N Chemical Research in Toxicology, doi: 10.1021/acs.chemrestox.2c00020 publication December 2009 Determination of tobacco-specific N-nitrosamines in urine of smokers and non-smokers Kavvadias D, Scherer G, Cheung F, Errington G, Shepperd J, McEwan M Biomarkers, Volume 14, doi: 10.3109/13547500903242883 publication March 2009 Simultaneous determination of four tobacco-specific N-nitrosamines (TSNA) in human urine Kavvadias D, Scherer G, Urban M, Cheung F, Errington G, Shepperd J, McEwan M Journal of Chromatography B, Volume 877, doi: 10.1016/j.jchromb.2009.03.009
N-Nitrosoanatabine (NAT)	NAT	Urine, ETS, Aerosol	LC-MS/MS, GC-MS	publication March 2022 Assessment of the Exposure to Tobacco-Specific Nitrosamines and Minor Tobacco Alkaloids in Users of Various Tobacco/Nicotine Products Scherer G, Scherer M, Mütze J, Hauke T, Pluym N Chemical Research in Toxicology, doi: 10.1021/acs.chemrestox.2c00020 publication December 2009 Determination of tobacco-specific N-nitrosamines in urine of smokers and non-smokers Kavvadias D, Scherer G, Cheung F, Errington G, Shepperd J, McEwan M Biomarkers, Volume 14, doi: 10.3109/13547500903242883 publication March 2009 Simultaneous determination of four tobacco-specific N-nitrosamines (TSNA) in human urine Kavvadias D, Scherer G, Urban M, Cheung F, Errington G, Shepperd J, McEwan M Journal of Chromatography B, Volume 877, doi: 10.1016/j.jchromb.2009.03.009
N-Nitrosonornicotine (NNN)	NNN	Urine, Plasma, Saliva, ETS, Aerosol	LC-MS/MS, GC-MS	publication March 2022 Assessment of the Exposure to NNN in the Plasma of Smokeless Tobacco Users Pluym N, Scherer G, Edmiston J, Jin X, Sarkar M, Scherer M Chemical Research in Toxicology, doi:10.1021/acs.chemrestox.1c00431 publication March 2022 Assessment of the Exposure to Tobacco-Specific Nitrosamines and Minor Tobacco Alkaloids in Users of Various Tobacco/Nicotine Products Scherer G, Scherer M, Mütze J, Hauke T, Pluym N Chemical Research in Toxicology, doi: 10.1021/acs.chemrestox.2c00020 publication December 2009 Determination of tobacco-specific N-nitrosamines in urine of smokers and non-smokers Kavvadias D, Scherer G, Cheung F, Errington G, Shepperd J, McEwan M Biomarkers, Volume 14, doi: 10.3109/13547500903242883 Conference contribution October 2019 NNN a suitable biomarker of exposure from smoke and new nicotine delivery products? Pluym N, Taucher J, Scherer G, Scherer M CORESTA SSPT 2019, Hamburg, Germany Conference contribution October 2021 Quantitative analysis of NNN in plasma by LC-MS/MS: a suitable alternative to urinary determination to assess the exposure to this important toxicant Pluym N, Sibul F, Jin X, Edmiston J, Sarkar M, Scherer G, Scherer M CORESTA SSPT 2021, Virtual publication March 2014 Saliva as a matrix for human biomonitoring in occupational and environmental medicine Michalke B, Rossbach B, Göen T, Schäferhenrich A, Scherer G International Archives of Occupational and Environmental Health, volume 88, doi: 10.1007/s00420-014-0938-5 publication March 2009 Simultaneous determination of four tobacco-specific N-nitrosamines (TSNA) in human urine Kavvadias D, Scherer G, Urban M, Cheung F, Errington G, Shepperd J, McEwan M Journal of Chromatography B, Volume 877, doi: 10.1016/j.jchromb.2009.03.009
NNK	Tobacco Smoke, Aerosol	ETS, Aerosol	LC-MS/MS
Norcotinine	Nicotine	Urine	LC-MS/MS	Conference contribution October 2013 Assessing the exposure to ‘smoke’ from electronic cigarettes by biomarkers Scherer G, Hagedorn H-W, Riedel K, Scherer M CORESTA SSPT 2013, Seville, Spain publication March 2019 Biomarkers of Exposure Specific to E-vapor Products Based on Stable-Isotope Labeled Ingredients Landmesser A, Scherer M, Pluym N, Sarkar M, Edmiston J, Niessner R, Scherer G Nicotine & Tobacco Research, Volume 21, doi: 10.1093/ntr/nty204 Conference contribution February 2018 Biomarkers of exposure specific to e-vapor products based on stable-isotope labeled ingredients Landmesser A, Scherer M, Scherer G, Sarkar M, Edmiston J, Pluym N SRNT 2018, Baltimore, USA Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients – methods Landmesser A, Pluym N, Scherer G, Sarkar M, Edmiston J, Scherer M CORESTA SSPT 2017, Kitzbühel, Austria Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients–results Landmesser A, Scherer M, Scherer G, Sarkar M, Edmiston J, Pluym N CORESTA SSPT 2017, Kitzbühel, Austria Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients–study design Landmesser A, Pluym N, Scherer G, Sarkar M, Edmiston J, Scherer M CORESTA SSPT 2017, Kitzbühel, Austria publication May 2018 Collaborative Method Performance Study of the Measurement of Nicotine, Its Metabolites, and Total Nicotine Equivalents in Human Urine Wang L, Bernert JT, Benowitz NL, Feng J, Jacob P 3rd, McGahee E, Caudill SP, Scherer G, Scherer M, Pluym N, Doig MV, Newland K, Murphy SE, Caron NJ, Sander LC, Shimizu M, Yamazaki H, Kim S, Langman LJ, Pritchett JS, Sniegoski LT, Li Y, Blount BC, Pirkle JL Cancer Epidemiology, Biomarkers & Prevention, Volume 27, doi: 10.1158/1055-9965 publication January 2014 Simple, fast and sensitive LC-MS/MS analysis for the simultaneous quantification of nicotine and 10 of its major metabolites Piller M, Gilch G, Scherer G, Scherer M Journal of Chromatography B, Volumes 951–952, doi: 10.1016/j.jchromb.2014.01.025 publication March 2022 Assessment of nicotine delivery and uptake in users of various tobacco / nicotine products Scherer G, Mütze J, Pluym N, Scherer M Current Research in Toxicology, Volume 3, 100067
Nornicotine	Nicotine	Urine	LC-MS/MS	Conference contribution October 2013 Assessing the exposure to ‘smoke’ from electronic cigarettes by biomarkers Scherer G, Hagedorn H-W, Riedel K, Scherer M CORESTA SSPT 2013, Seville, Spain publication March 2019 Biomarkers of Exposure Specific to E-vapor Products Based on Stable-Isotope Labeled Ingredients Landmesser A, Scherer M, Pluym N, Sarkar M, Edmiston J, Niessner R, Scherer G Nicotine & Tobacco Research, Volume 21, doi: 10.1093/ntr/nty204 Conference contribution February 2018 Biomarkers of exposure specific to e-vapor products based on stable-isotope labeled ingredients Landmesser A, Scherer M, Scherer G, Sarkar M, Edmiston J, Pluym N SRNT 2018, Baltimore, USA Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients – methods Landmesser A, Pluym N, Scherer G, Sarkar M, Edmiston J, Scherer M CORESTA SSPT 2017, Kitzbühel, Austria Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients–results Landmesser A, Scherer M, Scherer G, Sarkar M, Edmiston J, Pluym N CORESTA SSPT 2017, Kitzbühel, Austria Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients–study design Landmesser A, Pluym N, Scherer G, Sarkar M, Edmiston J, Scherer M CORESTA SSPT 2017, Kitzbühel, Austria publication May 2018 Collaborative Method Performance Study of the Measurement of Nicotine, Its Metabolites, and Total Nicotine Equivalents in Human Urine Wang L, Bernert JT, Benowitz NL, Feng J, Jacob P 3rd, McGahee E, Caudill SP, Scherer G, Scherer M, Pluym N, Doig MV, Newland K, Murphy SE, Caron NJ, Sander LC, Shimizu M, Yamazaki H, Kim S, Langman LJ, Pritchett JS, Sniegoski LT, Li Y, Blount BC, Pirkle JL Cancer Epidemiology, Biomarkers & Prevention, Volume 27, doi: 10.1158/1055-9965 publication January 2014 Simple, fast and sensitive LC-MS/MS analysis for the simultaneous quantification of nicotine and 10 of its major metabolites Piller M, Gilch G, Scherer G, Scherer M Journal of Chromatography B, Volumes 951–952, doi: 10.1016/j.jchromb.2014.01.025 publication March 2022 Assessment of nicotine delivery and uptake in users of various tobacco / nicotine products Scherer G, Mütze J, Pluym N, Scherer M Current Research in Toxicology, Volume 3, 100067
ortho-Toluidine	ortho-Toluidine	Urine, ETS	GC-MS	publication April 2006 Determination of three carcinogenic aromatic amines in urine of smokers and nonsmokers Riedel K, Scherer G, Engl J, Hagedorn H-W, Tricker AR Journal of Analytical Toxicology, Volume 30, doi: 10.1093/jat/30.3.187 publication November 2022 Assessment of the Exposure to Aromatic Amines in Users of Various Tobacco/Nicotine Products Gerhard Scherer, Kirsten Riedel, Nikola Pluym, Max Scherer ACS Omega, doi: 10.1021/acsomega.2c06130
para-Menthane-3,8-diol	Menthol	Plasma, Serum	LC-MS/MS
Particulate matter (PM)	Tobacco Smoke	Environmental Tobacco Smoke (ETS)	Light scattering or gravimetry
PGF2α	Oxidative Stress	Urine	LC-MS/MS	publication February 2012 A simple and robust UPLC-SRM/MS method to quantify urinary eicosanoids Sterz K, Scherer G, Ecker J Journal of Lipid Research, Volume 53, doi: 10.1194/jlr.D023739 publication March 2018 Analysis of Urinary Eicosanoids by LC-MS/MS Reveals Alterations in the Metabolic Profile after Smoking Cessation Goettel M, Niessner R, Scherer M, Scherer G, Pluym N Chemical Research in Toxicology, Volume 31, doi: 10.1021/acs.chemrestox publication October 2017 Metabolomic Fingerprinting in Various Body Fluids of a Diet-Controlled Clinical Smoking Cessation Study Using a Validated GC-TOF-MS Metabolomics Platform Goettel M, Niessner R, Mueller D, Scherer M, Scherer G, Pluym N Journal of Proteome Research, Volume 16(10), doi: 10.1021/acs.jproteome.7b00128. publication April 2018 Suitability of biomarkers of biological effects (BOBEs) for assessing the likelihood of reducing the tobacco related disease risk by new and innovative tobacco products: A literature review Scherer G Regulatory Toxicology and Pharmacology, Volume 94, doi: 10.1016/j.yrtph.2018.02.002
Phenantrene (Phe)	PAH	ETS	GC-MS
Propionaldehyde (PA)	Tobacco Smoke, E-Vapor Aerosol	ETS, e-liquids, aerosol	LC-MS/MS
Propylene glycol (PG)	Propylene glycol	Urine, Plasma, Serum, Saliva, PBS, Aerosol, ETS, e-liquids	LC-MS/MS	publication March 2019 Biomarkers of Exposure Specific to E-vapor Products Based on Stable-Isotope Labeled Ingredients Landmesser A, Scherer M, Pluym N, Sarkar M, Edmiston J, Niessner R, Scherer G Nicotine & Tobacco Research, Volume 21, doi: 10.1093/ntr/nty204 Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients–results Landmesser A, Scherer M, Scherer G, Sarkar M, Edmiston J, Pluym N CORESTA SSPT 2017, Kitzbühel, Austria Conference contribution September 2022 Propylene glycol as a specific biomarker for e-cigarette use Showcase of a novel Orbitrap-MS-based exposomics approach Nikola Pluym, Therese Burkhardt, Alpesh Kachhadia, Gerhard Scherer, Max Scherer ISES 2022, Lisbon Conference contribution March 2022 Propylene glycol: A Biomarker of Exposure specific to E-Cigarette Consumption Burkhardt T, Pluym N, Scherer G, Scherer M SRNT 2022, Baltimore (Hybrid), USA publication October 2021 1,2-Propylene Glycol: A Biomarker of Exposure Specific to e-Cigarette Consumption Burkhardt T, Pluym N, Scherer G, Scherer M Separations, 8, 180, doi: 10.3390/separations8100180
Prostaglandin D	Oxidative Stress	Urine	LC-MS/MS	publication February 2012 A simple and robust UPLC-SRM/MS method to quantify urinary eicosanoids Sterz K, Scherer G, Ecker J Journal of Lipid Research, Volume 53, doi: 10.1194/jlr.D023739 publication March 2018 Analysis of Urinary Eicosanoids by LC-MS/MS Reveals Alterations in the Metabolic Profile after Smoking Cessation Goettel M, Niessner R, Scherer M, Scherer G, Pluym N Chemical Research in Toxicology, Volume 31, doi: 10.1021/acs.chemrestox publication October 2017 Metabolomic Fingerprinting in Various Body Fluids of a Diet-Controlled Clinical Smoking Cessation Study Using a Validated GC-TOF-MS Metabolomics Platform Goettel M, Niessner R, Mueller D, Scherer M, Scherer G, Pluym N Journal of Proteome Research, Volume 16(10), doi: 10.1021/acs.jproteome.7b00128. publication April 2018 Suitability of biomarkers of biological effects (BOBEs) for assessing the likelihood of reducing the tobacco related disease risk by new and innovative tobacco products: A literature review Scherer G Regulatory Toxicology and Pharmacology, Volume 94, doi: 10.1016/j.yrtph.2018.02.002
Prostaglandin E	Oxidative Stress	Urine	LC-MS/MS	publication February 2012 A simple and robust UPLC-SRM/MS method to quantify urinary eicosanoids Sterz K, Scherer G, Ecker J Journal of Lipid Research, Volume 53, doi: 10.1194/jlr.D023739 publication March 2018 Analysis of Urinary Eicosanoids by LC-MS/MS Reveals Alterations in the Metabolic Profile after Smoking Cessation Goettel M, Niessner R, Scherer M, Scherer G, Pluym N Chemical Research in Toxicology, Volume 31, doi: 10.1021/acs.chemrestox publication October 2017 Metabolomic Fingerprinting in Various Body Fluids of a Diet-Controlled Clinical Smoking Cessation Study Using a Validated GC-TOF-MS Metabolomics Platform Goettel M, Niessner R, Mueller D, Scherer M, Scherer G, Pluym N Journal of Proteome Research, Volume 16(10), doi: 10.1021/acs.jproteome.7b00128. publication April 2018 Suitability of biomarkers of biological effects (BOBEs) for assessing the likelihood of reducing the tobacco related disease risk by new and innovative tobacco products: A literature review Scherer G Regulatory Toxicology and Pharmacology, Volume 94, doi: 10.1016/j.yrtph.2018.02.002
Pyrene (Pyr)	PAH	ETS	GC-MS
S-Benzylmercapturic acid (SBMA)	Toluene	Urine	LC-MS/MS	Conference contribution October 2014 Analysis of 18 Urinary Mercapturic Acids by two Multiplex-LC-MS/MS Methods Pluym N, Gilch G, Scherer G, Scherer M CORESTA Congress 2014, Quebec, Canada publication May 2015 Analysis of 18 urinary mercapturic acids by two high-throughput multiplex-LC-MS/MS methods Pluym N, Gilch G, Scherer G, Scherer M Analytical and Bioanalytical Chemistry, Volume 407, doi: 10.1007/s00216-015-8719-x publication October 2022 Comparison of urinary mercapturic acid excretions in users of various tobacco/nicotine products Gerhard Scherer, Nikola Pluym, Max Scherer Drug Testing and Analysis DOI: 10.1002/dta.3372
sICAM-1	Inflammation	Plasma	ELISA
Solanesol	Tobacco Smoke	Environmental Tobacco Smoke (ETS)	LC-MS
S-Phenylmercapturic acid (SPMA)	Benzene	Urine	LC-MS/MS	Conference contribution October 2014 Analysis of 18 Urinary Mercapturic Acids by two Multiplex-LC-MS/MS Methods Pluym N, Gilch G, Scherer G, Scherer M CORESTA Congress 2014, Quebec, Canada publication May 2015 Analysis of 18 urinary mercapturic acids by two high-throughput multiplex-LC-MS/MS methods Pluym N, Gilch G, Scherer G, Scherer M Analytical and Bioanalytical Chemistry, Volume 407, doi: 10.1007/s00216-015-8719-x publication October 2020 Benzene metabolite SPMA and acrylamide metabolites AAMA and GAMA in urine of children and adolescents in Germany - human biomonitoring results of the German Environmental Survey 2014-2017 (GerES V) Schwedler G, Murawski A, Schmied-Tobies MIH, Rucic E, Scherer M, Pluym N, Scherer G, Bethke R, Kolossa-Gehring M Environmental Research, Volume 192, doi: 10.1016/j.envres.2020.110295 publication October 2022 Comparison of urinary mercapturic acid excretions in users of various tobacco/nicotine products Gerhard Scherer, Nikola Pluym, Max Scherer Drug Testing and Analysis DOI: 10.1002/dta.3372
Toluene	Tobacco Smoke	ETS	GC-MS
trans-3'-Hydroxycotinine (3-OH-Cot)	Nicotine	Urine, Plasma, Serum, Saliva	LC-MS/MS	Conference contribution October 2013 Assessing the exposure to ‘smoke’ from electronic cigarettes by biomarkers Scherer G, Hagedorn H-W, Riedel K, Scherer M CORESTA SSPT 2013, Seville, Spain publication March 2019 Biomarkers of Exposure Specific to E-vapor Products Based on Stable-Isotope Labeled Ingredients Landmesser A, Scherer M, Pluym N, Sarkar M, Edmiston J, Niessner R, Scherer G Nicotine & Tobacco Research, Volume 21, doi: 10.1093/ntr/nty204 Conference contribution February 2018 Biomarkers of exposure specific to e-vapor products based on stable-isotope labeled ingredients Landmesser A, Scherer M, Scherer G, Sarkar M, Edmiston J, Pluym N SRNT 2018, Baltimore, USA Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients – methods Landmesser A, Pluym N, Scherer G, Sarkar M, Edmiston J, Scherer M CORESTA SSPT 2017, Kitzbühel, Austria Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients–results Landmesser A, Scherer M, Scherer G, Sarkar M, Edmiston J, Pluym N CORESTA SSPT 2017, Kitzbühel, Austria Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients–study design Landmesser A, Pluym N, Scherer G, Sarkar M, Edmiston J, Scherer M CORESTA SSPT 2017, Kitzbühel, Austria publication May 2018 Collaborative Method Performance Study of the Measurement of Nicotine, Its Metabolites, and Total Nicotine Equivalents in Human Urine Wang L, Bernert JT, Benowitz NL, Feng J, Jacob P 3rd, McGahee E, Caudill SP, Scherer G, Scherer M, Pluym N, Doig MV, Newland K, Murphy SE, Caron NJ, Sander LC, Shimizu M, Yamazaki H, Kim S, Langman LJ, Pritchett JS, Sniegoski LT, Li Y, Blount BC, Pirkle JL Cancer Epidemiology, Biomarkers & Prevention, Volume 27, doi: 10.1158/1055-9965 publication March 2014 Saliva as a matrix for human biomonitoring in occupational and environmental medicine Michalke B, Rossbach B, Göen T, Schäferhenrich A, Scherer G International Archives of Occupational and Environmental Health, volume 88, doi: 10.1007/s00420-014-0938-5 publication January 2014 Simple, fast and sensitive LC-MS/MS analysis for the simultaneous quantification of nicotine and 10 of its major metabolites Piller M, Gilch G, Scherer G, Scherer M Journal of Chromatography B, Volumes 951–952, doi: 10.1016/j.jchromb.2014.01.025 publication February 2014 Untargeted metabolomic profiling in saliva of smokers and nonsmokers by a validated GC-TOF-MS method Mueller DC, Piller M, Niessner R, Scherer M, Scherer G Journal of Proteome Research, Volume 13, doi: 10.1021/pr401099r
trans-3'-Hydroxycotinine-glucuronide (3-OH-Cot-gluc)	Nicotine	Urine	LC-MS/MS	Conference contribution October 2013 Assessing the exposure to ‘smoke’ from electronic cigarettes by biomarkers Scherer G, Hagedorn H-W, Riedel K, Scherer M CORESTA SSPT 2013, Seville, Spain publication March 2019 Biomarkers of Exposure Specific to E-vapor Products Based on Stable-Isotope Labeled Ingredients Landmesser A, Scherer M, Pluym N, Sarkar M, Edmiston J, Niessner R, Scherer G Nicotine & Tobacco Research, Volume 21, doi: 10.1093/ntr/nty204 Conference contribution February 2018 Biomarkers of exposure specific to e-vapor products based on stable-isotope labeled ingredients Landmesser A, Scherer M, Scherer G, Sarkar M, Edmiston J, Pluym N SRNT 2018, Baltimore, USA Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients – methods Landmesser A, Pluym N, Scherer G, Sarkar M, Edmiston J, Scherer M CORESTA SSPT 2017, Kitzbühel, Austria Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients–results Landmesser A, Scherer M, Scherer G, Sarkar M, Edmiston J, Pluym N CORESTA SSPT 2017, Kitzbühel, Austria Conference contribution October 2017 Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients–study design Landmesser A, Pluym N, Scherer G, Sarkar M, Edmiston J, Scherer M CORESTA SSPT 2017, Kitzbühel, Austria publication May 2018 Collaborative Method Performance Study of the Measurement of Nicotine, Its Metabolites, and Total Nicotine Equivalents in Human Urine Wang L, Bernert JT, Benowitz NL, Feng J, Jacob P 3rd, McGahee E, Caudill SP, Scherer G, Scherer M, Pluym N, Doig MV, Newland K, Murphy SE, Caron NJ, Sander LC, Shimizu M, Yamazaki H, Kim S, Langman LJ, Pritchett JS, Sniegoski LT, Li Y, Blount BC, Pirkle JL Cancer Epidemiology, Biomarkers & Prevention, Volume 27, doi: 10.1158/1055-9965 publication January 2014 Simple, fast and sensitive LC-MS/MS analysis for the simultaneous quantification of nicotine and 10 of its major metabolites Piller M, Gilch G, Scherer G, Scherer M Journal of Chromatography B, Volumes 951–952, doi: 10.1016/j.jchromb.2014.01.025 publication March 2022 Assessment of nicotine delivery and uptake in users of various tobacco / nicotine products Scherer G, Mütze J, Pluym N, Scherer M Current Research in Toxicology, Volume 3, 100067
trans,trans-muconic acid (tt-MA)	Benzene	Urine	GC-MS
Trehalose	Trehalose	PBS	LC-MS/MS
UV-PM	Tobacco Smoke	Environmental Tobacco Smoke (ETS)	Photometry
Xylene	Tobacco Smoke	ETS	GC-MS

Pioniere in der Biomarker-Forschung

Alle im ABF entwickelten Biomarker-Methoden wurden in Fachzeitschriften mit Peer-Review-Verfahren veröffentlicht. Eine Tatsache, die die Validität, Transparenz und wissenschaftliche Evidenz der Bioanalytik untermauert. Dies ist vor allem für Zulassungsanträge bei Regulatoren von Bedeutung.